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Causes

By Mayo Clinic staff

There are different varieties of Staphylococcus aureus bacteria, commonly called "staph." Staph bacteria are normally found on the skin or in the nose of about one-third of the population. The bacteria are generally harmless unless they enter the body through a cut or other wound, and even then they usually cause only minor skin problems in healthy people.

According to the Centers for Disease Control and Prevention, about 1 percent of the population carries the type of staph bacteria known as MRSA.

Antibiotic resistance
MRSA is the result of decades of often unnecessary antibiotic use. For years, antibiotics have been prescribed for colds, flu and other viral infections that don't respond to these drugs. Even when antibiotics are used appropriately, they contribute to the rise of drug-resistant bacteria because they don't destroy every germ they target. Bacteria live on an evolutionary fast track, so germs that survive treatment with one antibiotic soon learn to resist others.

References
  1. Antimicrobial (drug) resistance: Methicillin-resistant Staphylococcus aureus (MRSA). National Institute of Allergy and Infectious Diseases. http://www3.niaid.nih.gov/topics/antimicrobialResistance/Examples/mrsa/overview.htm. Accessed March 16, 2010.
  2. Community-associated MRSA infection for the public. Centers for Disease Control and Prevention. http://www.cdc.gov/ncidod/dhqp/ar_mrsa_ca_public.html. Accessed March 16, 2010.
  3. Archer GL. Staphylococcal infections. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/189395219-4/968689922/1492/1112.html#4-u1.0-B978-1-4160-2805-5..50315-3--cesec33_13717. Accessed March 16, 2010.
  4. Antibiotic resistance: Questions and answers. Centers for Disease Control and Prevention. http://www.cdc.gov/getsmart/antibiotic-use/anitbiotic-resistance-faqs.html. Accessed March 16, 2010.
  5. Wallin TR, et al. Community-associated methicillin-resistant Staphylococcus aureus. Emergency Medicine Clinics of North America. 2008;26:431.
  6. Freeman J, et al. Rapid detection of methicillin-resistant Staphylococcus aureus. http://www.uptodate.com/home/index.html. Accessed March 16, 2010.
DS00735 May 29, 2010

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