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Risk factors

By Mayo Clinic staff

Because hospital and community strains of MRSA generally occur in different settings, the risk factors for the two strains differ.

Risk factors for community-associated MRSA (CA-MRSA)

  • Young age. CA-MRSA can be particularly dangerous in children. Often entering the body through a cut or scrape, MRSA can quickly cause a widespread infection. Children may be susceptible because their immune systems aren't fully developed or they don't yet have antibodies to common germs. Children and young adults are also much more likely to develop dangerous forms of pneumonia, which can result from CA-MRSA, than older people are.
  • Participating in contact sports. CA-MRSA has affected sports teams. The bacteria spread easily through cuts and abrasions and skin-to-skin contact.
  • Sharing towels or athletic equipment. CA-MRSA has spread among athletes sharing razors, towels, uniforms or equipment.
  • Having a weakened immune system. People with weakened immune systems, such as those living with HIV/AIDS, are more likely to have severe CA-MRSA infections.
  • Living in crowded or unsanitary conditions. Outbreaks of CA-MRSA have occurred in military training camps and in American and European prisons.
  • Association with health care workers. People who are in close contact with health care workers are at increased risk of serious staph infections.

In addition to these risk factors, CA-MRSA is also spreading through certain groups of gay men. A study published in the Annals of Internal Medicine found a new strain of MRSA spreading rapidly among gay men in Boston and San Francisco. For example, gay men in San Francisco were 13 times more likely to be infected than others in the city.

Risk factors for health care-associated MRSA (HA-MRSA)

  • A current or recent hospitalization. MRSA remains a concern in hospitals, where it can attack those most vulnerable — older adults and people with weakened immune systems, burns, surgical wounds or serious underlying health problems. This is particularly true if you have a hospital stay of more than 14 days. A 2007 report from the Association for Professionals in Infection Control and Epidemiology estimated that 46 out of every 1,000 people hospitalized are infected or colonized with MRSA.
  • Living in a long term care facility. MRSA is also prevalent in these facilities. Carriers of MRSA have the ability to spread it, even if they're not sick themselves.
  • Invasive devices. People who are on dialysis, are catheterized, or have feeding tubes or other invasive devices are at higher risk.
  • Recent antibiotic use. Treatment with fluoroquinolones (ciprofloxacin, ofloxacin or levofloxacin) or cephalosporin antibiotics can increase the risk of HA-MRSA.

DS00735

May 30, 2008

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