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Complications

By Mayo Clinic staff

In some cases, people with multiple sclerosis may also develop:

  • Muscle stiffness or spasms
  • Paralysis, most typically in the legs
  • Problems with bladder, bowel or sexual function
  • Mental changes, such as forgetfulness or difficulties concentrating
  • Depression
  • Epilepsy
Preparing for your appointment Risk factors
References
  1. Olek MJ. Epidemiology, risk factors and clinical features of multiple sclerosis in adults. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2010.
  2. Olek MJ. Treatment of relapsing-remitting multiple sclerosis in adults. http://www.uptodate.com/home/index.html. Accessed Sept. 29, 2010.
  3. Multiple sclerosis: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/multiple_sclerosis/detail_multiple_sclerosis.htm. Accessed Oct. 14, 2010.
  4. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Oct. 14, 2010.
  5. Burt RK, et al. Autologous non-myeloablative haemopoietic stem cell transplantation in relapsing-remitting multiple sclerosis: a phase I/II study. Lancet Neurology. 2009;8:244.
  6. Foley F, et al. Taming stress in multiple sclerosis. National Multiple Sclerosis Society. http://www.nationalmssociety.org/search-results/index.aspx?q=stress&x=0&y=0&start=0&num=20. Accessed Oct. 15. 2010.
  7. Harmon M. Exercise as part of everyday life. National Multiple Sclerosis Society. http://www.nationalmssociety.org/search-results/index.aspx?q=exercise&sitesearch=&x=0&y=0&start=0&num=20. Accessed Oct. 14, 2010.
  8. Medication guide: Gilenya. U.S. Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Label_ApprovalHistory. Accessed Oct. 20, 2010.
  9. Lucchinetti CF (expert opinion). Mayo Clinic, Rochester, Minn. Oct. 18, 2010.
  10. Baclofen. Micromedex Healthcare Series. http://www.micromedex.com. Accessed Nov. 23, 2010.
  11. Tizanidine hydrochloride. Micromedex Healthcare Series. http://www.micromedex.com. Accessed Nov. 23, 2010.
DS00188 Dec. 11, 2010

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