Myasthenia gravis

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Complications

By Mayo Clinic staff

Complications of myasthenia gravis are treatable, but some can be life-threatening.

Myasthenic crisis
Myasthenic crisis is a life-threatening condition, which occurs when the muscles that control breathing become too weak to do their jobs. Emergency treatment is needed to provide mechanical assistance with breathing. Medications and blood-filtering therapies help people recover from myasthenic crisis, so they can again breathe on their own.

Thymus tumors
About 15 percent of the people who have myasthenia gravis have a tumor in their thymus, a gland under the breastbone that is involved with the immune system. Most of these tumors are noncancerous.

Other disorders
People who have myasthenia gravis are also more likely to have the following problems:

  • Underactive or overactive thyroid. The thyroid gland, which is in the neck, secretes hormones that regulate your metabolism. If your thyroid is underactive, your body uses energy more slowly. An overactive thyroid makes your body use energy too quickly.
  • Pernicious anemia. This is a condition in which vitamin B-12 is not properly absorbed from the diet, leading to anemia or neurological problems.
References
  1. Myasthenia gravis fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/myasthenia_gravis/detail_myasthenia_gravis.htm. Accessed July 6, 2010.
  2. Howard J.F. Myasthenia gravis — A summary. Myasthenia Gravis Foundation. http://www.myasthenia.org/hp_clinicaloverview.cfm. Accessed July 9, 2010.
  3. Bird SJ. Clinical manifestations of myasthenia gravis. http://www.uptodate.com/home/index.html. Accessed July 7, 2010.
  4. Bird SJ. Diagnosis of myasthenia gravis. http://www.uptodate.com/home/index.html. Accessed July 7, 2010.
  5. Bird SJ. Treatment of myasthenia gravis. http://www.uptodate.com/home/index.html. Accessed July 7, 2010.
  6. Facts about plasmapheresis. Muscular Dystrophy Association. http://www.mdausa.org/publications/fa-plasmaph.html. Accessed July 9, 2010.
DS00375 Sept. 21, 2010

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