Myelodysplastic syndromes

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Symptoms

By Mayo Clinic staff

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Photograph showing thick pattern of red dots on lower leg 
Petechiae

Myelodysplastic syndromes rarely cause signs or symptoms in the early stages of the disease. In time, myelodysplastic syndromes may cause:

  • Fatigue
  • Shortness of breath
  • Unusual paleness (pallor) due to anemia
  • Easy or unusual bruising or bleeding
  • Pinpoint-sized red spots just beneath your skin caused by bleeding (petechiae)
  • Frequent infections

When to see a doctor
Make an appointment with your doctor if you have any signs or symptoms that worry you.

References
  1. Nguyen PL. The myelodysplastic syndromes. Hematology/Oncology Clinics of North America. 2009;23:675.
  2. Myelodysplastic syndromes treatment (PDQ) patient version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/myelodysplastic/patient/allpages/print. Accessed Sept. 2, 2009.
  3. Vardiman JW, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes. Blood. 2009;114:937.
  4. Foran JM, et al. Myelodysplastic syndromes. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:2235.
  5. Stone RM. How I treat patients with myelodysplastic syndromes. Blood. 2009;113:6296.
  6. DeAngelo DJ, et al. Myelodysplastic syndromes: Biology and treatment. In: Hoffman R, et al. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa.: Churchill Livingstone; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniq=158945000. Accessed Aug. 26, 2009.

DS00596

Oct. 13, 2009

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