Naegleria infection

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Symptoms

By Mayo Clinic staff

Naegleria infection causes a disease called primary amebic meningoencephalitis (muh-ning-go-un-sef-uh-LIE-tis). This disease causes brain inflammation and destruction of brain tissue.

Generally beginning within one to two weeks of exposure to the amoeba, signs and symptoms of naegleria infection may include:

  • A change in the sense of smell or taste
  • Fever
  • Sudden headache
  • Stiff neck
  • Sensitivity to light
  • Nausea and vomiting
  • Confusion
  • Loss of balance
  • Sleepiness
  • Seizures
  • Hallucinations

These signs and symptoms can progress rapidly. They typically lead to death within three to seven days.

When to see a doctor
Seek immediate medical attention if you develop a sudden onset of fever, headache, stiff neck and vomiting.

References
  1. Fact sheet: Naegleria infection. Centers for Disease Control and Prevention. http:www.cdc.gov/ncidod/dpd/parasites/naegleria/factsht_naegleria.htm. Accessed Jan. 7, 2010.
  2. Centers for Disease Control and Prevention and the Council of State and Territorial Epidemiologists Naegleria Workgroup. Primary amebic meningoencephalitis - Arizona, Florida and Texas, 2007. Mortality and Morbidity Weekly Report. 2008:21;573.
  3. Solaymani-Mohammadi S, et al. Naegleria fowleri. In: Long SS, et al. Principles and Practice of Pediatric Infectious Diseases. 3rd ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008. http://www.mdconsult.com/das/book/body/177544974-4/936603208/1679/273.html#4-u1.0-B978-0-443-06687-0..50272-1_4741. Accessed Jan. 7, 2010.
  4. Weisse ME, et al. Primary amebic meningoencephalitis. In: Kliegman RM, et al. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/177544974-4/936603208/1608/712.html#. Accessed Jan. 7, 2010.
  5. Leder K, et al. Free living amebas. http://www.uptodate.com/home/index.html. Accessed Jan. 7, 2010.
  6. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Jan. 8, 2010.
DS01066 March 31, 2010

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