Nasal polyps

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Risk factors

By Mayo Clinic staff

Any condition that contributes to chronic inflammation in your nasal passages or sinuses (chronic sinusitis), such as infections or allergies, may increase your risk of nasal polyps. Conditions often associated with nasal polyps include:

  • Asthma, a disease that causes inflammation and constriction of airways
  • Aspirin sensitivity, an allergy-like response to aspirin or other nonsteroidal anti-inflammatory drugs — such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve)
  • Allergic fungal sinusitis, an allergy to airborne fungi
  • Cystic fibrosis, a genetic disorder that results in the production and secretion of abnormal fluids, including thick mucus from nasal and sinus membranes
  • Churg-Strauss syndrome, a rare disease that causes the inflammation of blood vessels

Other risk factors include:

  • Age. Nasal polyps are more common in adults.
  • Family history. There is some evidence that you may inherit a gene or genes that make you more likely to develop nasal polyps.
References
  1. Fried M. Nasal polyps. Merck Manuals Online Medical Library: Home Edition for Patients and Caregivers. http://www.merck.com/mmhe/sec19/ch221/ch221h.html. Accessed Jan. 4, 2009.
  2. Staffel J, et al. Rhinology, nasal obstruction and sinusitis. In: Wax M, ed. Primary Care Otolaryngology. 2nd ed., e-format. Alexandria, Va.: American Academy of Otolaryngology - Head and Neck Surgery; 2004. http://www.entnet.org/EducationAndResearch/upload/Chapter-9-Rhinology-Nasal-Obstruction-and-Sinusitis.pdf. Accessed Jan. 7, 2009.
  3. Pawliczak R, et al. Pathogenesis of nasal polyps: An update. Current Allergy and Asthma Reports. 2005;5:463-471.
  4. Fried M. Nasal polyps. Merck Manuals Online Medical Library: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec08/ch091/ch091d.html. Accessed Jan. 4, 2009.
  5. Sinusitis. American Academy of Otolaryngology - Head and Neck Surgery. http://www.entnet.org/HealthInformation/Sinusitis.cfm. Accessed Jan. 10, 2009.
  6. Pillsbury HC III, et al. Nose and sinuses. Merck Manuals Online Medical Library: Home Edition for Patients and Caregivers. http://www.merck.com/mmhe/print/sec19/ch217/ch217c.html. Accessed Jan. 7, 2009.
  7. Fungal sinusitis. American Academy of Otolaryngology - Head and Neck Surgery. http://www.entnet.org/HealthInformation/Fungal-Sinusitis.cfm. Accessed Jan. 10, 2009.
  8. Haddad J Jr. Nasal polyps. In: Kliegman R, et al, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia: Saunders/Elsevier Inc.; 2007. http://www.mdconsult.com/das/book/body/116189915-2/0/1608/891.html. Accessed Jan. 10, 2009.
  9. Rosenfeld RM. Clinical practice guideline on adult sinusitis. Otolaryngology - Head and Neck Surgery. 2007;137:365-377.
  10. Tips to remember: What is allergy testing? American Academy of Allergy, Asthma & Immunology. http://www.aaaai.org/patients/publicedmat/tips/whatisallergytesting.stm. Accessed Jan. 10, 2009.
  11. Scadding GK. Comparison of medical and surgical treatment of nasal polyposis. Current Allergy and Asthma Reports. 2002;2:494-499.
  12. Sinus surgery. American Academy of Otolaryngology - Head and Neck Surgery. http://www.entnet.org/HealthInformation/SinusSurgery.cfm. Accessed Jan. 10, 2009.
  13. Tips for sinus sufferers. American Academy of Otolaryngology - Head and Neck Surgery. http://www.entnet.org/HealthInformation/tipsSinusSufferers.cfm. Accessed Jan. 10, 2009.

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Feb. 20, 2009

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