Risk factorsBy Mayo Clinic staff
Any condition that triggers chronic inflammation in your nasal passages or sinuses, such as infections or allergies, may increase your risk of developing nasal polyps. Conditions often associated with nasal polyps include:
- Asthma, a disease that causes overall airway inflammation and constriction
- An allergy-like response to aspirin or to pain relievers such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve)
- Allergic fungal sinusitis, an allergy to airborne fungi
- Cystic fibrosis, a genetic disorder that results in the production and secretion of abnormally thick, sticky fluids, including thick mucus from nasal and sinus membranes
- Churg-Strauss syndrome, a rare disease that causes the inflammation of blood vessels
Your family history also may play a role. There's some evidence that certain genetic variations associated with immune system function make you more likely to develop nasal polyps.
- Fried MP. Nasal polyps. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec08/ch091/ch091d.html. Accessed Nov. 12, 2010.
- Levine M. Nasal polyps. American rhinologic society. http://www.american-rhinologic.org/patientinfo.nasalpolyps.phtml. Accessed Nov. 10, 2010.
- Hamilos DL. Clinical manifestations, pathophysiology and diagnosis of chronic rhinosinusitis. http://www.uptodate.com/home/index.html. Accessed Nov. 10, 2010.
- Scadding GK, et al. BSACI guidelines for the management of rhinosinusitis and nasal polyposis. Clinical and Experimental Allergy. 2007;38:260.
- Antunes MB, et al. The role of local steroid injection for nasal polyposis. Current Asthma and Allergy Reports. 2010;10:175.
- Dykewicz MS, et al. Rhinitis and sinusitis. Journal of Allergy and Clinical Immunology. 2010;125(Suppl 2):S103.
- Wood AJ, et al. Pathogenesis and treatment of chronic rhinosinusitis. Postgraduate Medical Journal. 2010;86:359.
- Hamilos DL. Medical management of chronic rhinosinusitis. http://www.uptodate.com/home/index.html. Accessed Nov. 10, 2010.
- Tosun F, et al. Impact of endoscopic sinus surgery on sleep quality in patients with chronic nasal obstruction due to nasal polyposis. The Journal of Craniofacial Surgery. 2009;20:446.
- Citardi MJ. An introduction to nasal endoscopy. American Rhinologic Society. http://www.american-rhinologic.org/patientinfo.introendoscopy.phtml. Accessed Nov. 10, 2010.
- Dutton JM. Endoscopic sinus surgery. American Rhinologic Society. http://www.american-rhinologic.org/patientinfo.sinussurgery.phtml. Accessed Nov. 19, 2010.
- Li JT (expert opinion). Mayo Clinic, Rochester, Minn. Nov. 23, 2010.
- Rabago D, et al. Nasal irrigation for chronic sinus symptoms in patients with allergic rhinitis, asthma, and nasal polyposis: A hypothesis generating study. Wisconsin Medical Journal. 2008;107:69.