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  • With Mayo Clinic asthma and allergy specialist

    James T C Li, M.D., Ph.D.

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Question

Nasal spray addiction: Is it real?

I use an over-the-counter nasal spray for congestion associated with allergies. Should I be concerned about nasal spray addiction?

Answer

from James T C Li, M.D., Ph.D.

What you may be referring to is a rebound effect that can occur if you use over-the-counter nasal decongestant sprays regularly. After a few days of using this type of nasal spray, your nose may become less responsive to the effects of the medication.

As a result, you may need to use more and more of the medication to control congestion or your congestion may worsen if you stop using the medication. Some people may mistake this rebound effect for "addiction," but it isn't.

True addiction is a compulsive physiological need for and use of a habit-forming substance known to be physically, psychologically or socially harmful. Over-the-counter nasal sprays don't cause the physiological cravings that mark an addiction.

To prevent rebound congestion, use over-the-counter decongestant nasal sprays for no more than five days in a row, with as few doses as possible each day. Prescription nasal sprays containing steroids don't cause this rebound effect, so they can be used on a daily basis for years.

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References
  1. Fletcher RH. An overview of rhinitis. http://uptodate.com/home/index.html. Accessed Dec. 9, 2011.
  2. Orban NT, et al. Allergic and non-allergic rhinitis. In: Adkinson NF, et al. Middleton's Allergy Principles and Practice. Philadelphia, Pa.: Mosby Elsevier; 2008. http://www.mdconsult.com/das/book/body/167892717-3/909560603/1806/59.html#4-u1.0-B978-0-323-05659-5..00055-3--s0140_1848. Accessed Dec. 9, 2011.
  3. Understanding drug abuse and addiction. National Institute on Drug Abuse. http://drugabuse.gov/infofacts/understand.html. Accessed Dec. 9, 2011.
  4. Li JT (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 14, 2011.
AN01241 Feb. 10, 2012

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