Nasopharyngeal carcinoma

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Definition

By Mayo Clinic staff

Living with cancer newsletter

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Nasopharyngeal (nay-zo-fuh-RIN-gee-uhl) carcinoma is cancer that occurs in the nasopharynx, which is located behind your nose and above the back of your throat.

Nasopharyngeal carcinoma is rare in the United States. In other parts of the world — specifically Asia and northern Africa — nasopharyngeal carcinoma occurs much more frequently.

Nasopharyngeal carcinoma is difficult to detect early, probably because the nasopharnyx isn't easy to examine and symptoms of nasopharyngeal carcinoma mimic those of many other conditions. Your main treatment options for nasopharyngeal carcinoma are radiation therapy, chemotherapy or a combination of the two. You can work with your doctor to determine the exact approach depending on your particular situation.

References
  1. Tan L, et al. Benign and malignant tumors of the nasopharynx. In: Flint PW, et al. Cummings Otolaryngology: Head & Neck Surgery. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05283-2..X0001-8--TOP&isbn=978-0-323-05283-2&uniq=203948673#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-323-05283-2..X0001-8--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-0-323-05283-2%3Btype%3DbookHome. Accessed June 2, 2010.
  2. Head and neck cancers. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/head-and-neck.pdf. Accessed June 2, 2010.
  3. Nasopharyngeal cancer treatment. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/nasopharyngeal/healthprofessional/allpages. Accessed June 2, 2010.
  4. Caponigro F, et al. Treatment approaches to nasopharyngeal carcinoma: A review. Anti-Cancer Drugs. 2010;21:471.
  5. Hui EP, et al. Epidemiology, etiology and diagnosis of nasopharyngeal carcinoma. http://www.uptodate.com/home/index.html. Accessed June 14, 2010.
  6. Paraneoplastic syndromes information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/paraneoplastic/paraneoplastic.htm. June 14, 2010.
  7. Couch ME. History, physical examination and the preoperative evaluation. Cummings Otolaryngology: Head & Neck Surgery. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05283-2..X0001-8--TOP&isbn=978-0-323-05283-2&uniq=203948673#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-323-05283-2..X0001-8--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-0-323-05283-2%3Btype%3DbookHome. Accessed June 14, 2010.
  8. Hui EP, et al. Treatment of locoregional nasopharyngeal carcinoma. http://www.uptodate.com/home/index.html. Accessed June 14, 2010.
  9. Dry mouth or xerostomia. Cancer.Net. http://www.cancer.net/patient/All+About+Cancer/Treating+Cancer/Managing+Side+Effects/Dry+Mouth+or+Xerostomia. Accessed June 11, 2010.
  10. Oral complications of chemotherapy and head/neck radiation. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/supportivecare/oralcomplications/patient/allpages. Accessed June 2, 2010.
DS00756 July 10, 2010

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