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Symptoms

By Mayo Clinic staff

Signs and symptoms of nephrotic syndrome include:

  • Swelling (edema), particularly around your eyes and in your ankles and feet
  • Foamy urine, which may be caused by excess protein in your urine
  • Weight gain due to excess fluid retention

When to see a doctor
Make an appointment with your doctor if you have any signs or symptoms that worry you.

Causes Definition
References
  1. Nephrotic syndrome in adults. National Institute of Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/KUDiseases/pubs/nephrotic/index.aspx. Accessed Dec. 15, 2011.
  2. Nachman PH, et al. Primary glomerular disease. In: Brenner BM. Brenner & Rector's The Kidney. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2008. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-1-4160-3105-5..X5001-4--TOP&isbn=978-1-4160-3105-5&uniqId=230100505-57. Accessed Dec. 16, 2011.
  3. Childhood nephrotic syndrome. National Institute for Diabetes and Digestive and Kidney Diseases. http://kidney.niddk.nih.gov/kudiseases/pubs/childkidneydiseases/nephrotic_syndrom/index.htm. Accessed Dec. 15, 2011.
  4. Kelepouris E, et al. Overview of heavy proteinuria and the nephrotic syndrome. http://www.uptodate.com/home/index.html. Accessed Dec. 16, 2011.
  5. Nephrotic syndrome. In: Ferri FF. Ferri's Clinical Advisor 2012: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-323-05611-3..C2009-0-38601-8--TOP&isbn=978-0-323-05611-3&uniqId=291436269-101. Accessed Dec. 15, 2011.
  6. Nephrotic syndrome. ADA Nutrition Care Manual. http://nutritioncaremanual.org/index.cfm. Accessed Dec. 15, 2011.
  7. Anderson CF (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 17, 2011.
DS01047 Jan. 11, 2012

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