Mayo Clinic Health Manager
Get free personalized health guidance for you and your family.
Get StartedSymptoms
By Mayo Clinic staffSigns and symptoms of neuroblastoma vary depending on what part of the body is affected.
Neuroblastoma in the abdomen — the most common form — may cause signs and symptoms such as:
- Abdominal pain
- A feeling of fullness in the abdomen
- A mass under the skin that isn't tender when touched
- Changes in bowel habits, such as constipation
- Changes in urinary habits, such as having to go to the bathroom more often
- Swelling in the legs
Neuroblastoma in the chest may cause signs and symptoms such as:
- Wheezing
- Swelling in the face
- Changes to the eyes, including drooping eyelids and unequal pupil size
Other signs and symptoms that may indicate neuroblastoma include:
- Lumps of tissue under the skin
- Eyeballs that seem to protrude from the sockets (proptosis)
- Dark circles, similar to bruises, around the eyes
- Back pain
- Curvature of the spine (scoliosis)
- Fever
- Unexplained weight loss
- Bone pain
When to see a doctor
Contact your child's doctor if your child has any signs or symptoms that worry you. Mention any changes in your child's behavior or habits.