Tests and diagnosis
By Mayo Clinic staffDiagnosis is typically based on your skin's appearance and a history of itching and scratching. Your doctor may recommend one of the following tests to rule out other causes or to confirm the diagnosis.
- Patch testing. A patch test (contact delayed hypersensitivity allergy test) can rule out other causes of itchy skin, such as allergic contact dermatitis. During a patch test, small quantities of potential allergens are applied to small patches, which are then placed on your skin. The patches remain on your skin for two days, and then your doctor checks for a reaction. If you're allergic to a particular substance being tested, you develop a raised bump or a reaction limited to the skin just beneath the patch.
- Punch biopsy. During a punch biopsy test, the doctor uses a circular tool to remove a small section of your skin's deeper layers. You may receive stitches to close the wound. A biopsy can rule out other conditions, such as lichen planus, that may mimic neurodermatitis.
References
- Lichen simplex chronicus. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec10/ch114/ch114f.html. Accessed March 17, 2010.
- Burgin S. Nummular eczema and lichen simplex chronicus/prurigo nodularis. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: McGraw-Hill Medical; 2003. http://www.accessmedicine.com/content.aspx?aID=2961069. Accessed March 17, 2010.
- Lichon V, et al. Lichen simplex chronicus. Dermatology Nursing. 2007;19:276.
- Berger TG. Dermatologic disorders. In: McPhee SJ, et al. Current Medical Diagnosis and Treatment. 49th ed. New York, N.Y.: McGraw-Hill Medical; 2010. http://www.accessmedicine.com/content.aspx?aID=747. Accessed March 17, 2010.
- Witch hazel. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed March 17, 2010.
- Camphor. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed March 17, 2010.
- Shenefelt PD. Hypnosis in dermatology. Archives of Dermatology. 2000;136:393.
- Gibson LE (expert opinion). Mayo Clinic, Rochester, Minn. March 22, 2010.

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