Nickel allergy

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Symptoms

By Mayo Clinic staff

If you have nickel allergy and you're exposed to a nickel-containing item, the allergic reaction (contact dermatitis) usually begins within 12 to 48 hours after exposure. The reaction may persist for as long as two to four weeks. The features of contact dermatitis usually appear only where your skin came into contact with nickel, but they may appear elsewhere on your body. Nickel allergy symptoms include:

  • Rash or bumps on the skin
  • Itching, which may be severe
  • Redness or changes in skin color
  • Dry patches of skin that may resemble a burn
  • Blisters and draining fluid in severe cases

Sweating at the point of contact with nickel may worsen the symptoms.

When to see a doctor
If you have a skin rash and don't know how you got it, talk to your doctor. If you've already been diagnosed with nickel allergy and are sure you're reacting to nickel exposure, use the over-the-counter treatments and home remedies your doctor has recommended in the past. However, if these treatments don't help, call your doctor. If you think the area may have become infected, see your doctor right away. Signs and symptoms that might indicate an infection include pain, increased redness, warmth or pus in the affected area.

References
  1. Schram SE, et al. Nickel hypersensitivity: A clinical review and call to action. International Journal of Dermatology. 2010;49:115.
  2. Beltrani VS. Contact dermatitis: A practice parameter. Annals of Allergy, Asthma and Immunology. 2006;97:s1.
  3. Douglas JD. Allergic contact dermatitis: A focus on nickel. Dermatology Nursing. 2009;21:354.
  4. Tips to remember: Allergic skin conditions. American Academy of Allergy, Asthma & Immunology. http://www.aaaai.org/patients/publicedmat/tips/allergicskinconditions.stm. Accessed June 13, 2010.
  5. Lu LK, et al. Prevention of nickel allergy: The case for regulation? Dermatology Clinic. 2009;27:155.
  6. Body art. Centers for Disease Control and Prevention. http://www.cdc.gov/niosh/topics/bbp/bodyart/stateRegs.html. Accessed June 13, 2010.
  7. Tattoos and body piercings. American Academy of Dermatology. http://www.aad.org/media/background/factsheets/fact_tattoos.html. Accessed June 13, 2010.
DS00826 Oct. 2, 2010

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