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Tests and diagnosis
By Mayo Clinic staffYour doctor can usually diagnose nickel allergy based on your:
- Skin's appearance
- Recent history of contact with items that may contain nickel
If the cause of your rash isn't apparent, however, your doctor may recommend a patch test (contact hypersensitivity allergy test). He or she may refer you to an allergy specialist (allergist) or a skin specialist (dermatologist) for this test.
Patch testing
During a patch test, very small quantities of potential allergens (including nickel) are applied to small patches, which are then placed on your skin to check for a reaction. The patches remain on your skin for two days before the doctor removes them. If you have a nickel allergy, the skin under the nickel patch will be inflamed when the patch is removed or in the days after removal of the patch.
Because of the low concentrations of allergens used, patch tests are safe even for people with severe allergies.
- Schram SE, et al. Nickel hypersensitivity: A clinical review and call to action. International Journal of Dermatology. 2010;49:115.
- Beltrani VS. Contact dermatitis: A practice parameter. Annals of Allergy, Asthma and Immunology. 2006;97:s1.
- Douglas JD. Allergic contact dermatitis: A focus on nickel. Dermatology Nursing. 2009;21:354.
- Tips to remember: Allergic skin conditions. American Academy of Allergy, Asthma & Immunology. http://www.aaaai.org/patients/publicedmat/tips/allergicskinconditions.stm. Accessed June 13, 2010.
- Lu LK, et al. Prevention of nickel allergy: The case for regulation? Dermatology Clinic. 2009;27:155.
- Body art. Centers for Disease Control and Prevention. http://www.cdc.gov/niosh/topics/bbp/bodyart/stateRegs.html. Accessed June 13, 2010.
- Tattoos and body piercings. American Academy of Dermatology. http://www.aad.org/media/background/factsheets/fact_tattoos.html. Accessed June 13, 2010.
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