CausesBy Mayo Clinic staff
Numbness in a hand is usually caused by damage, irritation or compression of one of the nerves or a branch of one of the nerves in your arm and wrist.
Diseases affecting the peripheral nerves, such as diabetes, also can cause numbness, although this is often preceded by similar symptoms in your feet.
Rarely, numbness can be caused by problems in your brain or spinal cord, although this is usually accompanied by weakness or loss of function in your arm or hand. Fortunately, numbness by itself is only rarely associated with potentially life-threatening disorders, such as strokes or tumors.
Your doctor will need detailed information about your symptoms to diagnose the cause of your numbness. A variety of tests may be needed to confirm the cause before appropriate treatment can begin.
Possible causes of numbness in one or both of your hands include:
- Brachial plexus injury
- Carpal tunnel syndrome
- Cervical spondylosis
- Ganglion cysts
- Guillain-Barre syndrome
- Lyme disease
- Multiple sclerosis
- Paraneoplastic syndromes of the nervous system
- Peripheral neuropathy
- Raynaud's disease
- Side effects of chemotherapy drugs
- Sjogren's syndrome
- Spinal cord injury
- Type 2 diabetes
- Ulnar nerve compression
- Vitamin B-12 deficiency
Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.
- Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Feb. 1, 2013.
- Stroke: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/stroke/detail_stroke.htm. Accessed Feb. 1, 2013.
- Rosenfeld J, et al. Numbness: A practical guide for family physicians. American Academy of Neurology. http://www.aan.com/go/education/curricula/family/chapter3/section1. Accessed Feb. 2, 2013.
- Raynaud's disease. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/raynaud/ray_all.html. Accessed Feb. 1, 2013.
- Numbness. National Multiple Sclerosis Society. http://www.nationalmssociety.org/about-multiple-sclerosis/what-we-know-about-ms/symptoms/numbness/index.aspx. Accessed Feb. 1, 2013.
- Neuropathy (nerve damage). American Diabetes Association. http://www.diabetes.org/living-with-diabetes/complications/neuropathy/. Accessed Feb. 1, 2013.
- Stabler SP. Vitamin B12 deficiency. New England Journal of Medicine. 2013;368:149.
- Cervical spondylosis (arthritis of the neck). American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00369. Accessed Feb. 4, 2013.
- Ganglion (cyst) of the wrist. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00006. Accessed Feb. 4, 2013.
- Syrinx. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/print/sec16/ch224/ch224j.html. Accessed Feb. 4, 2013.