Causes
By Mayo Clinic staffPossible causes of numbness in one or both of your hands include:
- Alcoholism
- Amyloidosis (when substances called amyloid proteins build up in your organs)
- Brachial plexus injury (an injury to the network of nerves that conducts signals from the spine to the shoulder, arm and hand)
- Carpal tunnel syndrome
- Cervical spondylosis (age-related wear and tear affecting the disks in your neck)
- Type 2 diabetes
- Ganglion cysts (noncancerous fluid-filled lumps that most commonly develop along the tendons or joints of your wrists or hands)
- Guillain-Barre syndrome (an uncommon disorder in which your body's immune system attacks your nerves)
- HIV/AIDS
- Lyme disease (a tick-borne illness)
- Paraneoplastic syndromes of the nervous system (a group of rare disorders that develop in some people with cancer)
- Peripheral neuropathy (nerve damage that often causes numbness and pain in your hands and feet)
- Raynaud's disease (a condition that causes some areas of your body to feel numb and cool in response to cold temperatures or stress)
- Side effects of chemotherapy drugs
- Sjogren's syndrome (an autoimmune disease that causes dry eyes and dry mouth)
- Spinal cord injury
- Stroke
- Syphilis
- Syringomyelia (the development of a fluid-filled cyst, or syrinx, within your spinal cord)
- Ulnar nerve compression
- Vasculitis (an inflammation of your blood vessels)
- Vitamin B-12 deficiency
Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis.
References
- Rosenfeld J, et al. Numbness: A practical guide for family physicians. American Academy of Neurology. http://www.aan.com/familypractice/pdf/FINAL%20NUMBNESS%203.pdf. Accessed Feb. 1, 2011.
- Briemberg HR, et al. Approach to the patient with sensory loss. http://www.uptodate.com/home/index.html. Accessed Feb. 1, 2011.
- Amyloidosis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec12/ch160/ch160a.html. Accessed Feb. 2, 2011.
- NINDS brachial plexus injuries information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/brachial_plexus/brachial_plexus.htm. Accessed Feb. 1, 2011.
- Cervical spondylosis (arthritis of the neck). American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00369. Accessed Feb. 1, 2011.
- Ganglion (cyst) of the wrist. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00006. Accessed Feb. 3, 2011.
- Peripheral neuropathy fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/peripheralneuropathy/detail_peripheralneuropathy.htm. Accessed Feb. 3, 2011.
- NINDS Paraneoplastics syndrome information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/paraneoplastic/paraneoplastic.htm. Accessed Feb. 5, 2011.
- Raynaud's syndrome. American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=4687. Accessed Feb. 5, 2011.
- About Sjogren's syndrome. Sjogren's Syndrome Foundation. http://www.sjogrens.org/home/about-sjogrens-syndrome. Accessed Feb. 3, 2011.
- Syrinx. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/print/sec16/ch224/ch224j.html. Accessed Feb. 4, 2011.
- Carpal tunnel syndrome fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/carpal_tunnel/detail_carpal_tunnel.htm. Accessed Feb. 3, 2011.
- Vasculitis. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/dci/Diseases/vas/vas_whatis.html 2/. Accessed Feb. 6, 2011.
- What you need to know about stroke. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/stroke/stroke_needtoknow.htm. Accessed Feb. 5, 2011.

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