NuvaRing (vaginal ring)

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Risks

By Mayo Clinic staff

The vaginal ring doesn't offer protection from sexually transmitted infections (STIs).

An estimated 5 out of 100 women will get pregnant in the first year of using NuvaRing.

Side effects of NuvaRing may include:

  • An increased risk of blood-clotting problems, heart attack, stroke, liver cancer, gallbladder disease and high blood pressure
  • Breakthrough bleeding or spotting
  • Fluid retention
  • Vaginal infection or irritation
  • Vaginal secretion
  • Headache
  • Nausea
  • Weight gain
  • Depression
  • Decreased sex drive
  • Breast tenderness

Call your health care provider as soon as possible if you have:

  • Breast lumps
  • Foul vaginal odor or vaginal itching
  • Irregular vaginal bleeding during more than one menstrual cycle
  • New or worsening headaches
  • Signs or symptoms of a blood clot in your leg, such as persistent pain in your calf
  • Signs or symptoms of toxic shock syndrome, such as a sudden fever, vomiting, diarrhea, dizziness, fainting or a rash
  • Signs or symptoms of jaundice, such as yellowing of the skin or whites of the eyes, especially with fever, fatigue, loss of appetite, dark urine or light-colored bowel movements
  • Signs or symptoms of depression, such as trouble sleeping, fatigue or feeling sad
  • Two missed periods or other signs of pregnancy
References
  1. Combined (estrogen & progestin) contraceptives. In: Zieman M, et al. A Pocket Guide to Managing Contraception. Tiger, Ga.: Bridging the Gap Foundation; 2010:114.
  2. Zieman M. Overview of contraception. http://www.uptodate.com/home/index.html. Accessed Nov. 18, 2011.
  3. Birth control methods fact sheet. U.S. Department of Health and Human Services. http://www.womenshealth.gov/publications/our-publications/fact-sheet/birth-control-methods.cfm. Accessed Nov. 18, 2011.
  4. Implants, injections, rings, and patches: Hormonal birth control options. American College of Obstetricians and Gynecologists. http://www.acog.org/publications/faq/faq159.cfm. Accessed Nov. 18, 2011.
  5. Nanda K. Contraceptive patch and vaginal contraceptive ring. In: Hatcher RA, et al. Contraceptive Technology. 20th ed. New York, N.Y.: Ardent Media; 2011.
  6. NuvaRing (prescribing information). Roseland, N.J.: Organon USA Inc.; 2008. http://www.nuvaring.com/hcp/global/prescribing-information.asp. Accessed Nov. 18, 2011.
  7. NuvaRing. U.S. Food and Drug Administration. http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.DrugDetails. Accessed Nov. 18, 2011.
MY01008 Jan. 21, 2012

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