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Complications

By Mayo Clinic staff

Complications arising from optic neuritis may include:

  • Optic nerve damage. Most people have some permanent optic nerve damage following an episode of optic neuritis, but they may not have any symptoms resulting from this damage.
  • Decreased visual acuity. Most people regain normal or near normal vision within several months, but for some people, vision loss may persist even after the optic neuritis has improved.
  • Side effects of treatment. Steroid medications used to treat optic neuritis subdue your immune system, which causes your body to become more susceptible to infections. Long-term use of steroids may also cause thinning of your bones (osteoporosis).
References
  1. Balcer LJ. Optic neuritis. The New England Journal of Medicine. 2006;354:1273.
  2. Clark D, et al. Optic neuritis. Neurologic Clinics. 2010;28:573.
  3. Dargin JM, et al. The painful eye. Emergency Medical Clinics of North America. 2008;26:199.
  4. Osborne B. Optic neuritis: Pathophysiology, clinical features, and diagnosis. http://www.uptodate.com/home/index.html. Accessed Dec. 28, 2010.
  5. Graves J, et al. Eye disorders in patients with multiple sclerosis: Natural history and management. Clinical Ophthalmology. 2010;4:1409.
  6. Riordan-Eva P. Disorders of the eyes & lids. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment 2011. New York, N.Y.: McGraw-Hill Medical; 2011. http://www.accessmedicine.com/content.aspx?aID=2002. Accessed Jan. 1, 2011.
  7. Ropper AH, et al. Disturbances of vision. In: Ropper AH, et al. Adams and Victor's Principles of Neurology. 9th ed. New York, N.Y.: McGraw-Hill Medical; 2009. http://www.accessmedicine.com/content.aspx?aID=3631567. Accessed Jan. 1, 2011.
  8. Germann CA, et al. Ophthalmic diagnoses in the ED: Optic neuritis. American Journal of Emergency Medicine. 2007;25:834.
  9. Chan RYC, et al. Ocular toxicity of ethambutol. Hong Kong Medical Journal. 2006;12:56.
  10. Osborne B. Optic neuritis: Prognosis and treatment. http://www.uptodate.com/home/index.html. Accessed Dec. 28, 2010.
  11. Robertson DM (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 10, 2011.
DS00882 Feb. 12, 2011

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