About our e-newsletters
- Free e-newsletters
- Mayo Clinic expertise
- We do not share your e-mail address
Housecall, our weekly general-interest e-newsletter, keeps you up to date on a wide variety of health topics with timely, reliable, practical information, recipes, blogs, questions and answers with Mayo Clinic experts and more. Our biweekly topic-specific e-newsletters also include blogs, questions and answers with Mayo Clinic experts, and other useful information that will help you manage your health.
Housecall Archives
Mayo Clinic Housecall
Stay up to date on the latest health information.
What you get
- Free weekly e-newsletter
- Mayo Clinic expertise
- Recipes, tools and other helpful information
- We do not share your e-mail address
Causes
By Mayo Clinic staff
Throat cancer occurs when cells in your throat develop genetic mutations. These mutations cause cells to grow uncontrollably and continue living after healthy cells would normally die. The accumulating cells can form a tumor in your throat.
It's not clear what causes the mutation that causes throat cancer. But doctors have identified factors that may increase your risk.
Types of throat cancer
Throat cancer is a general term that applies to cancer that develops in the throat (pharyngeal cancer) or in the voice box (laryngeal cancer). The throat and the voice box are closely connected, with the voice box located just below the throat. More specific terms to describe the types of throat cancer include:
- Nasopharyngeal cancer begins in the nasopharynx — the part of your throat just behind your nose.
- Oropharyngeal cancer begins in the oropharynx — the part of your throat right behind your mouth that includes your tonsils.
- Hypopharyngeal cancer (laryngopharyngeal cancer) begins in the hypopharynx (laryngopharynx) — the lower part of your throat, just above your esophagus and windpipe.
- Glottic cancer begins in the vocal cords.
- Supraglottic cancer begins in the upper portion of the larynx and includes cancer that affects the epiglottis, which is a piece of cartilage that blocks food from going into your windpipe.
- Subglottic cancer begins in the lower portion of your voice box, below your vocal cords.
- Quon H. Cancer of the head and neck. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2007:1177.
- Armstrong WB, et al. Malignant tumors of the larynx. In: Flint PW, et al. Cummings Otolaryngology: Head & Neck Surgery. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05283-2..X0001-8--TOP&isbn=978-0-323-05283-2&uniq=203948673#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-323-05283-2..X0001-8--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-0-323-05283-2%3Btype%3DbookHome. Accessed June 16, 2010.
- Uppaluri R, et al. Neoplasms of the hypopharynx and cervical esophagus. In: Flint PW, et al. Cummings Otolaryngology: Head & Neck Surgery. 5th ed. Philadelphia, Pa.: Mosby Elsevier; 2010. http://www.mdconsult.com/book/player/book.do?method=display&type=aboutPage&decorator=header&eid=4-u1.0-B978-0-323-05283-2..X0001-8--TOP&isbn=978-0-323-05283-2&uniq=203948673#lpState=open&lpTab=contentsTab&content=4-u1.0-B978-0-323-05283-2..X0001-8--TOP%3Bfrom%3Dcontent%3Bisbn%3D978-0-323-05283-2%3Btype%3DbookHome. Accessed June 16, 2010.
- Head and neck cancers. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/head-and-neck.pdf. Accessed June 2, 2010.
- Laryngeal cancer treatment. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/laryngeal/patient/allpages. Accessed June 2, 2010.
- Hypopharyngeal cancer treatment. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/laryngeal/patient/allpages. Accessed June 2, 2010.
- Oropharyngeal cancer treatment. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/oropharyngeal/patient/allpages. Accessed June 2, 2010.
- What you need to know about cancer of the larynx. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/larynx/allpages. Accessed June 2, 2010.
- Erbitux (prescribing information). Branchburg, N.J.: ImClone Systems Incorporated; 2009. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/125084s167lbl.pdf. Accessed June 17, 2010.
- Freedman ND, et al. Fruit and vegetable intake and head and neck cancer risk in a large United States prospective cohort study. International Journal of Cancer. 2008;122:2330.
- Tonsils and adenoids. American Academy of Otolaryngology-Head and Neck Surgery. http://www.entnet.org/HealthInformation/tonsilsAdenoids.cfm. Accessed June 29, 2010.
Find Mayo Clinic on