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Complications

By Mayo Clinic staff

Oral thrush is seldom a problem for healthy children and adults, although the infection may return even after it's been treated. For people with compromised immune systems, such as from HIV or cancer, however, thrush can be more serious.

If you have a compromised immune system:

  • Thrush is more likely to spread to other parts of your body, including your digestive tract, lungs and liver.
  • You may have especially severe symptoms in your mouth or esophagus, which can make eating painful and difficult.
  • The infection can spread to the intestines, making it difficult to receive adequate nutrition.
References
  1. Candidiasis. Centers for Disease Control and Prevention. http://www.cdc.gov/nczved/divisions/dfbmd/diseases/candidiasis/. Accessed April 25, 2011.
  2. Candidiasis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec10/ch120/ch120b.html. Accessed April 26, 2011.
  3. Lustig LR, et al. Ear, nose, & throat disorders. In: McPhee SJ, et al. Current Medical Diagnosis and Treatment 2011. 50th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=2613. Accessed April 25, 2011.
  4. Candidiasis. American Academy of Pediatrics Redbook. http://aapredbook.aappublications.org. Accessed April 27, 2011.
  5. Kauffman CA. Clinical manifestations of oropharyngeal and esophageal candidiasis. http://www.uptodate.com/home/index.html. Accessed April 21, 2011.
  6. Is thrush causing my sore nipples? La Leche League International. http://www.llli.org/FAQ/thrush.html. Accessed June 29, 2009.
  7. Diabetes and oral health. American Dental Association. http://www.ada.org/sections/scienceAndResearch/pdfs/patient_18.pdf. Accessed April 21, 2011.
  8. Clarkson JE, et al. Interventions for preventing oral candidiasis for patients with cancer receiving treatment. Cochrane Database of Systematic Reviews. 2007;(1): CD003807.
  9. Pienaar ED, et al. Interventions for the prevention and management of oropharyngeal candidiasis associated with HIV infection in adults and children. Cochrane Database of Systematic Reviews. 2010;(11):CD003940.
DS00408 Aug. 20, 2011

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