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Causes

By Mayo Clinic staff

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Illustration of male reproductive system 
Male reproductive system

Orchitis can be caused by either a bacterial or viral infection.

Bacterial orchitis
Most often, bacterial orchitis is the result of epididymitis, an inflammation of the coiled tube that connects the vas deferens and the testicle. The vas deferens carries sperm from your testicles. When inflammation in the epididymis spreads to the testicle, the resulting condition is known as epididymo-orchitis.

Epididymitis usually is caused by an infection of the urethra or bladder that spreads to the epididymis. Often the cause of the infection is a sexually transmitted infection (STI), particularly gonorrhea or chlamydia. Other causes of infection may be related to having been born with abnormalities in your urinary tract or having had a catheter or medical instruments inserted into your penis.

Viral orchitis
Most cases of viral orchitis are the result of the mumps virus. About one-third of males who contract the mumps after puberty develop orchitis during their course of the mumps, usually four to seven days after onset.

References
  1. Orchitis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/genitourinary_disorders/penile_and_scrotal_disorders/orchitis.html#v1058924. Accessed Sept. 10, 2011.
  2. Trojian T. et al. Epididymitis and orchitis: An overview. American Family Physician. 2009;79:583. http://www.aafp.org/afp/20090401/583.html. Accessed Sept. 10, 2011.
  3. Stewart A, et al. Epididymo-orchitis. BMJ. 2011;342:1.
  4. Corrales-Medina VF, et al. Viral & rickettsial infections. In: McPhee SJ, et al. Current Medical Diagnosis & Treatment 2011. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=17051. Sept. 10, 2011.
  5. Epididymitis and orchitis. American Urological Association. http://www.urologyhealth.org/urology/index.cfm?article=114. Accessed Sept. 10, 2011.
  6. Nicks BA, et al. Male genital problems. In: Tintinalli JE, et al. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=6362635. Sept. 10, 2011.
DS00602 Oct. 7, 2011

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