Osteomyelitis


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Causes

By Mayo Clinic staff

Most cases of osteomyelitis are caused by staphylococcus bacteria, a type of germ commonly found on the skin or in the nose of even healthy individuals.

Germs can enter a bone in a variety of ways, including:

  • Via the bloodstream. Germs in other parts of your body — for example, from pneumonia or a urinary tract infection — can travel through your bloodstream to a weakened spot in a bone. In children, osteomyelitis most commonly occurs in the softer areas, called growth plates, at either end of the long bones of the arms and legs.
  • From a nearby infection. Severe puncture wounds can carry germs deep inside your body. If such an injury becomes infected, the germs can spread into a nearby bone.
  • Direct contamination. This may occur if you have broken a bone so severely that part of it is sticking out through your skin. Direct contamination can also occur during surgeries to replace joints or repair fractures.
References
  1. Chihara S, et al. Osteomyelitis. Disease-a-Month. 2010;56:6.
  2. Longo DL, et al. Harrison's Online. 18th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=4. Accessed Oct. 1, 2012.
  3. Humphries RL, et al. Current Diagnosis & Treatment Emergency Medicine. 7th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=55756409. Accessed Oct. 1, 2012.
  4. Lalani T. Overview of osteomyelitis in adults. http://www.uptodate.com/index. Accessed Sept. 21, 2012.
  5. Ray CG, et al. Sherris Medical Microbiology. 5th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/content.aspx?aID=6950257. Accessed Oct. 1, 2012.
  6. Sia IG, et al. Osteomyelitis. Best Practice & Research Clinical Rheumatology. 2006; 20:1065.
  7. Infections. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00197. Accessed Oct. 5, 2012.
DS00759 Nov. 20, 2012

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