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By Mayo Clinic staffThe infection that causes osteomyelitis can usually be controlled. But a risk of recurrence always remains. Osteomyelitis that returns or continues undetected for years is considered chronic osteomyelitis. Chronic osteomyelitis can lead to the death of bone tissue and the collapse of the bone.
Osteomyelitis that can't be controlled may require drastic treatment in order to prevent spread to other parts of your body. When this occurs in arms and legs, drastic treatment may mean amputation of the affected limb.