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Definition
By Mayo Clinic staffOsteomyelitis is the medical term for an infection in a bone. Infections can reach a bone by traveling through the bloodstream or spreading from nearby tissue. Osteomyelitis can also begin in the bone itself if an injury exposes the bone to germs.
In children, osteomyelitis most commonly affects the long bones of the legs and upper arm, while adults are more likely to develop osteomyelitis in the bones that make up the spine (vertebrae). People who have diabetes may develop osteomyelitis in their feet if they have foot ulcers.
Once considered an incurable condition, osteomyelitis can be successfully treated today. Most people require surgery to remove parts of the bone that have died — followed by strong antibiotics, often delivered intravenously, typically for at least six weeks.
- Fort GG, et al. Osteomyelitis. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby Elsevier; 2009. http://www.mdconsult.com/das/book/body/191358793-4/974051922/2088/463.html#4-u1.0-B978-0-323-05609-0..00024-1--sc0070_9510. Accessed March 26, 2010.
- Chihara S, et al. Osteomyelitis. Disease-a-Month. 2010;56:6.
- Lalani T. Overview of osteomyelitis in adults. http://www.uptodate.com/home/index.html. Accessed March 26, 2010.
- Infections. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00197. Accessed March 26, 2010.
- Berbari EF, et al. Osteomyelitis. In: Mandell GL, et al. Mandell, Douglas and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-0-443-06839-3..00103-X&uniq=191840490&isbn=978-0-443-06839-3#lpState=opened&lpTab=contentsTab&content=4-u1.0-B978-0-443-06839-3..00103-X%3Btype%3DbookPage%3Bisbn%3D978-0-443-06839-3. Accessed March 29, 2010.
- Dabov DB. Amputation for osteomyelitis. In: Canale ST, et al. Campbell's Operative Orthopaedics. 11th ed. Philadelphia, Pa.: Mosby Elsevier; 2007. http://www.mdconsult.com/das/book/body/191847540-7/0/1584/111.html?tocnode=55686605&fromURL=111.html. Accessed March 29, 2010.
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