Definition
By Mayo Clinic staffOsteoporosis causes bones to become weak and brittle — so brittle that a fall or even mild stresses like bending over or coughing can cause a fracture. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine.
Bone is living tissue, which is constantly being absorbed and replaced. Osteoporosis occurs when the creation of new bone doesn't keep up with the removal of old bone.
Osteoporosis affects men and women of all races. But white and Asian women — especially those who are past menopause — are at highest risk. Medications, healthy diet and weight-bearing exercise can help prevent bone loss or strengthen already weak bones.
- Osteoporosis: Handout on health. NIH Osteoporosis and Related Bone Diseases National Resource Center. http://www.niams.nih.gov/Health_Info/Bone/Osteoporosis/osteoporosis_hoh.asp. Accessed March 25, 2013.
- Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed March 25, 2013.
- Bope ET, et al. Conn's Current Therapy. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.mdconsult.com/books/about.do?about=true&eid=$eid&isbn=978-1-4557-0295-4&uniqId=398813857-1936. Accessed March 25, 2013.
- Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed March 25, 2013.
- Kennel KA (expert opinion). Mayo Clinic, Rochester, Minn. March 26, 2013.
- Rosen HN. Bisphosphonates in the management of osteoporosis in postmenopausal women. http://www.uptodate.com/home. Accessed March 26, 2013.
- Finkelstein JS. Treatment of osteoporosis in men. http://www.uptodate.com/home. Accessed March 26, 2013.
- Rosen CJ. Parathyroid hormone therapy for osteoporosis. http://www.uptodate.com/home. Accessed March 26, 2013.
- Rosen HN. Denosumab for osteoporosis. http://www.uptodate.com/home. Accessed March 26, 2013.
- Calcium. Office of Dietary Supplements. National Institutes of Health. http://ods.od.nih.gov/factsheets/Calcium-HealthProfessional. Accessed March 26, 2013.
- Ask Mayo Expert. Vitamin D deficiency. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2012.
- Vitamin D. Office of Dietary Supplements. National Institutes of Health. http://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional. Accessed March 26, 2013.


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