Paget's disease of bone

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Definition

By Mayo Clinic staff

Paget's disease of bone is a condition affecting how your bone breaks down and rebuilds. Healthy bone metabolism allows for old bone to be recycled into new bone throughout your life.

In Paget's disease of bone, the rate at which old bone is broken down and new bone is formed is distorted. Over time, Paget's disease of bone may result in your bones becoming fragile and misshapen.

Paget's disease of bone is more common with age. Many older people with discomfort in their bones and joints assume the discomfort is a natural part of aging, and don't seek treatment. But to prevent the most serious complications of Paget's disease of bone, it's important to get treatment as soon as possible after symptoms appear.

DS00485

Aug. 15, 2008

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