Paget's disease of bone

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Risk factors

By Mayo Clinic staff

Factors that can increase your risk of Paget's disease of bone include:

  • Age. People older than 40 are the most likely to develop Paget's disease of bone.
  • Sex. Men are more commonly affected than are women.
  • National origin. Paget's disease of bone is more common in England, Scotland, central Europe and Greece — as well as countries settled by European immigrants. It's uncommon in Scandinavia and Asia.
  • Family history. If you have a close relative who has Paget's disease of bone, you are much more likely to develop the condition yourself.
Complications Causes
References
  1. Paget's disease of bone. National Institutes of Health Osteoporosis and Related Bone Diseases: National Resource Center. http://www.niams.nih.gov/health_info/Pagets/default.asp. Accessed Dec. 11. 2012.
  2. Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 11, 2012.
  3. Paget's disease of bone. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00076. Accessed Dec. 11, 2012.
  4. Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Dec. 11, 2012.
  5. Seton M. Clinical manifestations and diagnosis of Paget disease of bone. http://www.uptodate.com/index. Accessed Dec. 11, 2012.
  6. Firestein GS, et al. Kelley's Textbook of Rheumatology. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.mdconsult.com/das/book/body/208746819-6/0/1807/0.html. Accessed Dec. 11, 2012.
  7. Seton M. Treatment of Paget disease of bone. http://www.uptodate.com/index. Accessed Dec. 11, 2012.
  8. Nippoldt TB (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 14, 2013.
  9. Rosen HN. Bisphosphonates in the management of osteoporosis in postmenopausal women. http://www.uptodate.com/index. Accessed Jan. 15, 2013.
DS00485 Feb. 13, 2013

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