Risk factors
By Mayo Clinic staffFactors that can increase your risk of Paget's disease of bone include:
- Age. People older than 40 are the most likely to develop Paget's disease of bone.
- Sex. Men are more commonly affected than are women.
- National origin. Paget's disease of bone is more common in England, Scotland, central Europe and Greece — as well as countries settled by European immigrants. It's uncommon in Scandinavia and Asia.
- Family history. If you have a close relative who has Paget's disease of bone, you are much more likely to develop the condition yourself.
References
- Paget's disease of bone. National Institutes of Health Osteoporosis and Related Bone Diseases: National Resource Center. http://www.niams.nih.gov/health_info/Pagets/default.asp. Accessed Dec. 11. 2012.
- Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Dec. 11, 2012.
- Paget's disease of bone. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=a00076. Accessed Dec. 11, 2012.
- Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Dec. 11, 2012.
- Seton M. Clinical manifestations and diagnosis of Paget disease of bone. http://www.uptodate.com/index. Accessed Dec. 11, 2012.
- Firestein GS, et al. Kelley's Textbook of Rheumatology. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2013. http://www.mdconsult.com/das/book/body/208746819-6/0/1807/0.html. Accessed Dec. 11, 2012.
- Seton M. Treatment of Paget disease of bone. http://www.uptodate.com/index. Accessed Dec. 11, 2012.
- Nippoldt TB (expert opinion). Mayo Clinic, Rochester, Minn. Jan. 14, 2013.
- Rosen HN. Bisphosphonates in the management of osteoporosis in postmenopausal women. http://www.uptodate.com/index. Accessed Jan. 15, 2013.


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