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Symptoms
By Mayo Clinic staffMost people who have Paget's disease of bone experience no symptoms. When symptoms do occur, the most common complaint is bone pain. The disease may affect only one or two areas of your body, or may be widespread. Your signs and symptoms, if any, will depend on the part of your body that's affected, including:
- Pelvis. Paget's disease of bone in the pelvis can cause hip pain.
- Skull. An overgrowth of bone in the skull can cause hearing loss or headaches.
- Spine. If your spine is affected, nerve roots can become compressed. This can cause pain, tingling and numbness in an arm or leg.
- Leg. As the bones weaken, they may bend — causing you to become bow-legged. Enlarged and misshapen bones in your legs can put extra stress on nearby joints, which may cause wear-and-tear arthritis in your knee or hip.
When to see a doctor
Talk to your doctor if you have:
- Pain in your bones and joints
- Tingling and weakness
- Bone deformities
- Facts a new patient needs to know about Paget's disease of bone. National Institutes of Health Osteoporosis and Related Bone Diseases: National Resource Center. http://www.niams.nih.gov/health_info/bone/pagets/default.asp. Accessed May 26, 2010.
- Roodman GD. Paget's disease of bone. In: Goldman L, et al. Cecil Medicine. 23rd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/203002646-3/1004517503/1492/963.html#4-u1.0-B978-1-4160-2805-5..50273-1_12206. Accessed May 26, 2010.
- Paget's disease of bone. American Academy of Orthopaedic Surgeons. http://orthoinfo.aaos.org/topic.cfm?topic=A00076. Accessed May 26, 2010.
- Mercier LR. Paget's disease of the bone. In: Ferri FF. Ferri's Clinical Advisor 2010. Philadelphia, Pa.: Mosby Elsevier; 2009. http://www.mdconsult.com/das/book/body/203002646-3/1004517503/2088/470.html#4-u1.0-B978-0-323-05609-0..00025-3--sc0010_9669. Accessed May 26, 2010.
- Kelepouris N. Clinical manifestations and diagnosis of Paget disease of bone. http://www.uptodate.com/home/index.html. Accessed May 27, 2010.
- Lane NE. Paget's disease of bone. In: Firestein GS, et al. Kelley's Textbook of Rheumatology. 8th ed. Philadelphia, Pa.: WB Saunders Co.; 2008. http://www.mdconsult.com/das/book/body/203002646-3/0/1807/698.html?tocnode=55733939&fromURL=698.html#4-u1.0-B978-1-4160-3285-4..10092-0--s0210_3402. Accessed May 26, 2010.
- Seton M. Treatment of Paget disease of bone. http://www.uptodate.com/home/index.html. Accessed May 27, 2010.
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