Pancreas transplant

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By Mayo Clinic staff

Choosing a transplant center
If your doctor recommends a pancreas transplant, you'll be referred to a transplant center. You're also free to select a transplant center on your own or choose a center from your insurance company's list of preferred providers.

When considering transplant centers, you may want to:

  • Learn about the number and type of transplants the center performs each year
  • Ask about the transplant center's organ donor and recipient survival rates
  • Compare transplant center statistics through the database maintained by the Scientific Registry of Transplant Recipients (www.ustransplant.org)
  • Consider additional services provided by the transplant center, such as support groups, travel arrangements, local housing for your recovery period and referrals to other resources

After you've selected a transplant center, you'll need an evaluation to determine whether you meet the center's eligibility requirements for a pancreas transplant.

The team at the transplant center will assess whether you:

  • Are healthy enough to have surgery and tolerate lifelong post-transplant medications
  • Have any medical conditions that would hinder transplant success
  • Are willing and able to take medications as directed

If you need a kidney transplant, too, the transplant team will also determine if it's best for you to have the pancreas and kidney transplants during the same surgery, or a kidney transplant first, followed by the pancreas transplant at a later date. The best option depends on the severity of your kidney damage, the availability of donors and your preference.

Once you've been accepted as a candidate for a pancreas transplant, your name will be placed on a national list of people awaiting a transplant. The waiting time for a transplant depends on your blood group and how long it takes for a suitable donor — one whose blood and tissue types match yours — to become available.

Staying healthy
Whether you're waiting for a donated pancreas to become available or your transplant surgery is already scheduled, it's important to keep your mind and body healthy.

  • Take your medications as prescribed.
  • Follow your diet and exercise guidelines.
  • Keep all appointments with your health care team.
  • Stay involved in healthy activities, including relaxing and spending time with family and friends.

If you're waiting for a donated pancreas, make sure the transplant team knows how to reach you at all times and arrange transportation to the transplant center in advance.

References
  1. Humar A, et al. Transplantation. In: Brunicardi FC, et al. Schwartz's Principles of Surgery. 8th ed. New York, N.Y.: McGraw-Hill Companies; 2005. http://www.accessmedicine.com/content.aspx?aID=799511. Accessed June 24, 2009.
  2. Robertson RP. Patient selection for and immunologic issues related to kidney-pancreas transplantation in diabetes mellitus. http://www.uptodate.com/home/index.html. Accessed June 25, 2009.
  3. Pancreas Kaplan-Meier graft survival rates for transplants performed 1997-2004, by diagnosis. Organ Procurement and Transplantation Network. http://optn.transplant.hrsa.gov/latestData/rptStrat.asp. Accessed July 5, 2009.
  4. Facts about pancreas transplants. American Society of Transplantation. http://www.a-s-t.org/files/pdf/patient_education/english/AST-EdBroPANCREAS-ENG.pdf. Accessed June 30, 2009.
  5. American Diabetes Association position statement: Pancreas and islet transplantation in type 1 diabetes. Diabetes Care. 2006;29:935.
  6. Getting a kidney-pancreas transplant. National Kidney Foundation. http://www.kidney.org/atoz/atozItem.cfm?id=159. Accessed June 24, 2009.
  7. Robertson RP. Benefits and complications associated with kidney-pancreas transplantation in diabetes mellitus. http://www.uptodate.com/home/index.html. Accessed June 25, 2009.
  8. Larson-Wadd K, et al. Pancreas and islet cell transplantation. Anesthesiology Clinics of North America. 2004;22:663.
  9. Coping with the physical side effects of anti-rejection medications. American Society of Transplantation. http://www.healthytransplant.com/index.php?q=quality_of_life/coping_with_the_physical_side_effect_of_anti-rejection_medications. Accessed July 5, 2009.
  10. Punch JD. Organ transplantation. In: Doherty GM, et al. Current Surgical Diagnosis & Treatment. 12th ed. New York, N.Y.: McGraw-Hill Companies; 2006. http://www.accessmedicine.com/content.aspx?aID=2066708. Accessed June 24, 2009.
  11. Robertson RP. Pancreas and islet transplantation in diabetes mellitus. http://www.uptodate.com/home/index.html. Accessed June 25, 2009.
  12. OPTN/SRTR annual report: Adjusted graft survival by year of transplant at 3 months, 1 year, 3 years, 5 years and 10 years, kidney-pancreas transplants — pancreas graft. Scientific Registry of Transplant Recipients. http://www.ustransplant.org/annual_reports/current/809b_kp.htm. Accessed July 7, 2009.
  13. OPTN/SRTR annual report: Adjusted graft survival by year of transplant at 3 months, 1 year, 3 years, 5 years and 10 years, pancreas after kidney (PAK) transplants. Scientific Registry of Transplant Recipients. http://www.ustransplant.org/annual_reports/current/709_pak.htm. Accessed July 7, 2009.
  14. OPTN/SRTR annual report: Adjusted graft survival by year of transplant at 3 months, 1 year, 3 years, 5 years and 10 years, pancreas transplant alone (PTA) transplants. Scientific Registry of Transplant Recipients. http://www.ustransplant.org/annual_reports/current/609_pta.htm. Accessed July 7, 2009.

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Sept. 22, 2009

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