Pancreas transplant

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Risks

By Mayo Clinic staff

Complications of the procedure
Pancreas transplant surgery carries a risk of significant complications, including:

  • Blood clots
  • Bleeding
  • Infection
  • Excess sugar in your blood (hyperglycemia)
  • Urinary complications, including leaking or urinary tract infections
  • Failure of the donated pancreas
  • Rejection of the donated pancreas

Anti-rejection medication side effects
After a pancreas transplant, you'll take medications for the rest of your life to help prevent your body from rejecting the donor pancreas. These medications can cause a variety of side effects, including:

  • Bone thinning
  • High cholesterol
  • High blood pressure
  • Skin sensitivity
  • Puffiness
  • Weight gain
  • Swollen gums
  • Acne
  • Excessive hair growth
References
  1. Robertson RP. Patient selection for and immunologic issues relating to kidney-pancreas transplantation in diabetes mellitus. http://www.uptodate.com/home/index.html. Accessed May 28, 2011.
  2. Facts about pancreas transplants. American Society of Transplantation. http://www.a-s-t.org/files/pdf/patient_education/english/AST-EdBroPANCREAS-ENG.pdf. Accessed May 29, 2011.
  3. Klein C, et al. Benefits and complications associated with kidney-pancreas transplantation in diabetes mellitus. http://www.uptodate.com/home/index.html. Accessed May 28, 2011.
  4. Pancreas transplantation. American Diabetes Association. http://www.diabetes.org/living-with-diabetes/treatment-and-care/transplantation/pancreas-transplantation.html. Accessed June 2, 2011.
  5. Robertson RP. Pancreas and islet transplantation in diabetes mellitus. http://www.uptodate.com/home/index.html. Accessed June 2, 2011.
  6. Humar A, et al. Transplantation. In: Brunicardi FC, et al. Schwartz's Principles of Surgery. 9th ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/content.aspx?aid=5012706. Accessed May 28, 2011.
  7. Health after transplantation. American Society of Transplantation. http://www.healthytransplant.com/health_maintenance/health_after_transplantation.aspx. Accessed June 5, 2011.
  8. Preparing for the transplant. American Society of Transplantation. http://www.healthytransplant.com/health_maintenance/preparing_for_transplant.aspx. Accessed June 5, 2011.
  9. Kidney-pancreas transplant. National Kidney Foundation. http://www.kidney.org/atoz/content/kidpantx.cfm. Accessed June 5, 2011.
  10. OPTN/SRTR annual report: Adjusted graft survival by year of transplant at 3 months, 1 year, 3 years, 5 years and 10 years, kidney-pancreas transplants — pancreas graft. Scientific Registry of Transplant Recipients. http://www.ustransplant.org/annual_reports/current/809b_kp.htm. Accessed May 29, 2011.
  11. OPTN/SRTR annual report: Adjusted graft survival by year of transplant at 3 months, 1 year, 3 years, 5 years and 10 years, pancreas after kidney (PAK) transplants. Scientific Registry of Transplant Recipients. http://www.ustransplant.org/annual_reports/current/709_pak.htm. Accessed May 29, 2011.
  12. OPTN/SRTR annual report: Adjusted graft survival by year of transplant at 3 months, 1 year, 3 years, 5 years and 10 years, pancreas transplant alone (PTA) transplants. Scientific Registry of Transplant Recipients. http://www.ustransplant.org/annual_reports/current/609_pta.htm. Accessed May 29, 2011.
MY00762 Sept. 22, 2011

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