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Causes

By Mayo Clinic staff

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Illustration showing pancreas 
Pancreas

Pancreatic cancer occurs when cells in your pancreas develop genetic mutations. These mutations cause the cells to grow uncontrollably and to continue living after normal cells would die. These accumulating cells can form a tumor.

Understanding your pancreas
Your pancreas is about 6 inches (15 centimeters) long and looks something like a pear lying on its side. The pancreas is a crucial part of your digestive system. It secretes hormones, including insulin, to help your body process sugar. And it produces digestive juices to help your body digest food.

Types of pancreatic cancer
The types of cells involved in a pancreatic cancer help determine the best treatment. Types of pancreatic cancer include:

  • Cancer that forms in the pancreas ducts (adenocarcinoma). Cells that line the ducts of the pancreas help produce digestive juices. The majority of pancreatic cancers are adenocarcinomas. Sometimes these cancers are called exocrine tumors.
  • Cancer that forms in the hormone-producing cells. Cancer that forms in the hormone-producing cells of the pancreas is called endocrine cancer. Endocrine cancers of the pancreas are very rare.

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April 12, 2008

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