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Risk factors

By Mayo Clinic staff

Living With Cancer

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Factors that may increase your risk of pancreatic cancer include:

  • Being African-American
  • Being overweight or obese
  • Chronic inflammation of the pancreas (pancreatitis)
  • Diabetes
  • Family history of genetic syndromes that can increase cancer risk, including a BRCA2 gene mutation, Lynch syndrome and familial atypical mole-malignant melanoma (FAMMM)
  • Personal or family history of pancreatic cancer
  • Smoking
References
  1. What you need to know about cancer of the pancreas. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/pancreas. Accessed Feb. 28, 2012.
  2. Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008:1595.
  3. Pancreatic adenocarcinoma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Feb. 28, 2012.
  4. Tarceva (prescribing information). Farmingdale, N.Y.: OSI Pharmaceuticals Inc.; 2011. http://www.tarceva.com/pancreatic/considering/index.jsp. Accessed March 5, 2012.
  5. Clark KL, et al. Psychological distress in patients with pancreatic cancer - An understudied group. Psycho-Oncology. 2010;19:1313.
  6. Distress management. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Feb. 28, 2012.
DS00357 April 10, 2012

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