Risk factors
By Mayo Clinic staffFactors that may increase your risk of pancreatic cancer include:
- Being African-American
- Being overweight or obese
- Chronic inflammation of the pancreas (pancreatitis)
- Diabetes
- Family history of genetic syndromes that can increase cancer risk, including a BRCA2 gene mutation, Lynch syndrome and familial atypical mole-malignant melanoma (FAMMM)
- Personal or family history of pancreatic cancer
- Smoking
References
- What you need to know about cancer of the pancreas. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/pancreas. Accessed Feb. 28, 2012.
- Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2008:1595.
- Pancreatic adenocarcinoma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Feb. 28, 2012.
- Tarceva (prescribing information). Farmingdale, N.Y.: OSI Pharmaceuticals Inc.; 2011. http://www.tarceva.com/pancreatic/considering/index.jsp. Accessed March 5, 2012.
- Clark KL, et al. Psychological distress in patients with pancreatic cancer - An understudied group. Psycho-Oncology. 2010;19:1313.
- Distress management. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Feb. 28, 2012.


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