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Mayo Clinic Housecall
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Risk factors
By Mayo Clinic staffFactors that may increase your risk of pancreatic cancer include:
- Increasing age, especially over age 60
- Being African-American
- Being overweight or obese
- Chronic inflammation of the pancreas (pancreatitis)
- Diabetes
- Family history of genetic syndromes that can increase cancer risk, including a BRCA2 gene mutation, Peutz-Jeghers syndrome, Lynch syndrome and familial atypical mole-malignant melanoma (FAMMM)
- Personal or family history of pancreatic cancer
- Smoking
References
- What you need to know about cancer of the pancreas. National Cancer Institute. http://www.cancer.gov/cancertopics/wyntk/pancreas/allpages. Accessed Feb. 17, 2010.
- Pancreatic cancer treatment (PDQ): Health professional version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/pancreatic/healthprofessional/allpages. Accessed Feb. 17, 2010.
- Drebin JA, et al. Carcinoma of the pancreas. In: Abeloff MD, et al. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingstone; 2008:1595.
- Freitas D, et al. Medical management of pancreatic adenocarcinoma. Pancreatology. 2009;9:223.
- Pancreatic adenocarcinoma. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/pancreatic.pdf. Accessed Feb. 17, 2010.
- Locker GY, et al. ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. Journal of Clinical Oncology. 2006;24:5313.
- Barbara Woodward Lips Patient Education Center. About your Whipple operation. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2006:17.
- Tarceva (prescribing information). Melville, N.Y.: OSI Pharmaceuticals Inc.; 2009. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021743s015lbl.pdf. Accessed Feb. 23, 2010.
- Pliarchopoulou K, et al. Pancreatic cancer: Current and future treatment strategies. Cancer Treatment Reviews. 2009;35:431.
- Clark KL, et al. Psychological distress in patients with pancreatic cancer - An understudied group. Psycho-Oncology. In press. Accessed Feb. 23, 2010.
- Distress management. Fort Washington, Pa.: National Comprehensive Cancer Network. http://www.nccn.org/professionals/physician_gls/PDF/distress.pdf. Accessed Feb. 23, 2010.
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