Paraneoplastic syndromes of the nervous system

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Risk factors

By Mayo Clinic staff

Any cancer may be associated with a paraneoplastic syndrome of the nervous system. However, the disorders occur more often in people with cancers of the lung, ovary, breast, testis or lymphatic system.

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References
  1. NINDS paraneoplastic syndrome information page. National Institutes of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/paraneoplastic/paraneoplastic.htm. Accessed Oct. 4, 2010.
  2. Dalmau J, et al. Paraneoplastic neurologic syndromes. In: Abeloff M, et al., eds. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa.: Churchill Livingston Elsevier; 2008. http://www.mdconsult.com/das/book/body/221079415-3/1062999853/1709/56.html#4-u1.0-B978-0-443-06694-8..50055-5--cesec11_1589. Accessed Oct. 4, 2010.
  3. Pelosof LC, et al. Paraneoplastic syndromes: An approach to diagnosis and treatment. Mayo Clinic Proceedings. 2010;85:838.
  4. Toothaker TB, et al. Paraneoplastic neurological syndromes: A review. Neurologist. Jan 2009;15:21.
  5. Dalmau J, et al. Paraneoplastic syndromes of the CNS. Lancet Neurology. 2008;7:327.
  6. Giglio P, et al. Neurologic complications of cancer and its treatment. Current Oncology Reports. 2010;12:50a.
  7. NINDS Isaac's syndrome information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/Isaacs_syndrome/Isaacs_syndrome.htm. Accessed Oct. 5, 2010.
  8. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Oct. 5, 2010.
  9. Therapeutic hematheresis. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec11/ch146/ch146f.html. Accessed Oct. 7, 2010.
  10. Passive immunization. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/sec14/ch169/ch169c.html?qt=immunoglobulin&alt=sh. Accessed Oct. 7, 2010.
  11. McKeon A, et al. Positron emission tomography-computed tomography in paraneoplastic neurologic disorders: Systematic analysis and review. Archives of Neurology. 2010;67:322.
  12. Pittock SJ, et al. Paraneoplastic Autoimmunity Affecting the Nervous System. In: Baehring JM, et al., eds. Brain Tumors: Practical Guide to Diagnosis and Management. New York, N.Y.: Informa Healthcare; 2007:515.
  13. Lachance DH, et al. Paraneoplastic neurological autoimmunity. In: Kalman B, et al., eds. Neuroimmunology in Clinical Practice. Hoboken, N.J.: Wiley-Blackwell; 2007:210.
  14. Harper CM, et al. Lambert-Eaton syndrome. In: Kaminski HJ. Current Clinical Neurology: Myasthenia Gravis and Related Disorders. Totowa, N.J.: Humana Press; 2009:269.
  15. Pittock SJ (expert opinion). Mayo Clinic, Rochester, Minn. Dec. 14, 2010.
DS00840 March 3, 2011

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