Definition
By Mayo Clinic staffParvovirus infection is a common and highly contagious childhood ailment — sometimes called slapped-cheek disease because of the distinctive face rash that develops. Parvovirus infection also has been known as fifth disease because, historically, it was one of five common childhood illnesses characterized by a rash.
In most children, parvovirus infection is mild and requires little treatment. However, parvovirus infection in some pregnant women can lead to serious health problems for the fetus. Parvovirus infection is also more serious for people with some kinds of anemia or who have a compromised immune system.
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- Jordan JA. Clinical manifestations and pathogenesis of human parvovirus B19 infection. http://www.uptodate.com/home/index.html. Accessed Oct. 22, 2009.
- Parvovirus B19 infection and erythema infectiosum. In: Cohen J, et al. Cohen & Powderly: Infectious Diseases. 2nd ed. Philadelphia, Pa.: Mosby Elsevier; 2004. http://www.mdconsult.com/das/book/body/166343766-3/906090993/1209/25.html#4-u1.0-B0-323-02407-6..50010-6--cesec37_250. Accessed Oct. 22, 2009.
- Riley LE, et al. Parvovirus B19 infection during pregnancy. http://www.uptodate.com/home/index.html. Accessed Oct. 22, 2009.
- Jordan JA. Treatment and prevention of parvovirus B19 infection. http://www.uptodate.com/home/index.html. Accessed Oct. 22, 2009.
- Reye's syndrome information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/reyes_syndrome/reyes_syndrome.htm. Accessed Oct. 22, 2009.

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