DefinitionBy Mayo Clinic staff
Patent ductus arteriosus (PDA) is a persistent opening between two major blood vessels leading from the heart. This normal connection, called the ductus arteriosus, is a necessary part of the baby's circulatory system before birth. It usually closes shortly after the baby is born. However, in some individuals it remains open (patent). When this occurs, it's called a patent ductus arteriosus.
A small patent ductus arteriosus often doesn't cause symptoms or problems and may never need treatment. Untreated, a large patent ductus arteriosus can cause too much poorly oxygenated blood to flow through the heart, weakening the heart muscle and causing heart failure and other complications.
Treatment options for repairing a patent ductus arteriosus include monitoring, medications, and closure by cardiac catheterization or surgery.
- Patent ductus arteriosus. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/pda/. Accessed Nov. 9, 2011.
- Patent ductus arteriosus. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/pediatrics/congenital_cardiovascular_anomalies/patent_ductus_arteriosus_pda.html?qt=patent%20ductus%20arteriosus&alt=sh. Accessed Nov. 9, 2011.
- Schneider DJ, et al. Patent ductus arteriosus. Circulation. 2006;114:1873.
- Doyle T, et al. Clinical manifestations and diagnosis of patent ductus arteriosus. http://www.uptodate.com/home/index.html. Accessed Nov. 9, 2011.
- Phillips III JB, et al. Pathophysiology, clinical manifestations, and diagnosis of patent ductus arteriosus in premature infants. http://www.uptodate.com/home/index.html Accessed Nov. 9, 2011.
- Miyamoto SD, et al. Cardiovascular diseases. In: Hay WW, et al, eds. Current Diagnosis & Treatment: Pediatrics. 20th ed. New York, N.Y.: The McGraw-Hill Companies; 2011. http://www.accessmedicine.com/content.aspx?aID=6582787. Accessed November 13, 2011.
- Patent ductus arteriosus (PDA). American Heart Association. http://www.heart.org/HEARTORG/Conditions/CongenitalHeartDefects/AboutCongenitalHeartDefects/Patent-Ductus-Arteriosis-PDA_UCM_307032_Article.jsp#.Trsm4fJUFI4. Accessed Nov. 9, 2011.
- Warnes CA, et al. ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelines on the management of adults with congenital heart disease). Journal of the American College of Cardiology. 2008;52:e143. Accessed Nov. 9, 2011.
- Clyburn RI, et al. Patent ductus arteriosus: Evidence for and against treatment. Journal of Pediatrics. 2007;150:216.
- Hammerman C, et al. Ductal closure with paracetamol: A surprising new approach to patent ductus arteriosus treatment. Pediatrics. In Press. Accessed Nov. 9, 2011.
- Preconception care questions and answers. U.S. Centers for Disease Control and Prevention. http://www.cdc.gov/ncbddd/preconception/QandA.htm. Accessed Nov. 14, 2011.