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Symptoms
By Mayo Clinic staffMost people with a patent foramen ovale don't know they have it, because it's usually a hidden condition that doesn't create signs or symptoms.
Rarely, an infant with a patent foramen ovale might have bluish skin (cyanosis) when crying or straining, such as when passing stool. When an infant with a patent foramen ovale has cyanosis, he or she usually has other heart defects.
- Atrial septal defect (ASD). American Heart Association. http://www.americanheart.org/presenter.jhtml?identifier=11065. Accessed April 22, 2010.
- Bashore TM, et al. Heart disease. In: McPhee SJ, et al. Current Medical Diagnosis and Treatment 2010. 49th ed. New York, N.Y.: McGraw-Hill; 2010. http://www.accessmedicine.com/content.aspx?aID=3671. Accessed April 22, 2010.
- Slottow TL, et al. Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on patent foramen ovale closure devices. Circulation 2007;116:677.
- O'Gara PT, et al. Percutaneous device closure of patent foramen ovale for secondary stroke prevention: A call for completion of randomized clinical trials — A science advisory from the American Heart Association/American Stroke Association and the American College of Cardiology Foundation. Circulation. 2009;119:2743.
- Johansson MC, et al. The significance of patent foramen ovale: A current review of associated conditions and treatment. International Journal of Cardiology. 2009;134:17.
- Specific cardiac defects. In: Libby P, et al. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/book/player/book.do?method=display&type=bookPage&decorator=header&eid=4-u1.0-B978-1-4160-4106-1..50064-9--cesec197&displayedEid=4-u1.0-B978-1-4160-4106-1..50064-9--cesec222&uniq=197042004&isbn=978-1-4160-4106-1&sid=987452515. Accessed April 22, 2010.
- Sommer RJ. Patent foramen ovale: Where are we in 2009? American Journal of Therapeutics. 2009;16:562.
- Rothrock JF. Patent foramen ovale (PFO) and migraine. Headache. 2008;48:1153.
- Meier B. Catheter-based closure of the patent foramen ovale. Circulation. 2009;120:1837.
- Grogan M (expert opinion). Mayo Clinic, Rochester, Minn. May 3, 2010
- Rosenow E (expert opinion). Mayo Clinic, Rochester, Minn. May 3, 2010.
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