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Peeling skin on hands: What causes it?

I have a problem. For the past few days, the skin on my hands and fingers has been peeling quite badly. What causes peeling skin on hands?

- Tom / Indiana

Mayo Clinic dermatologist Lawrence Gibson, M.D., and colleagues answer select questions from readers.

Answer

Peeling skin on hands typically is a temporary, harmless problem. It can have many causes, including:

  • Excessive perspiration and inadequate evaporation, most often when wearing gloves
  • Skin infections, such as fungal infections
  • Extremely dry skin — which can usually be remedied by using moisturizers, avoiding harsh soaps and using warm, rather than hot, water when washing your hands
  • Side effect of certain medications that cause skin drying, such as acne medications
  • Reaction to a medication, such as chemotherapy drugs or oral retinoids
  • Sunburn

Consult your doctor if you have extensive or unexplained skin peeling or if peeling continues for more than a couple of weeks. Rarely, peeling skin can be a sign of a serious underlying disorder, such as Kawasaki disease.

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May 13, 2008