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Definition

By Mayo Clinic staff

Pemphigus is a group of rare skin disorders that cause blisters of your skin or mucous membranes, such as in your mouth or on your genitals.

There are two main types: pemphigus vulgaris and pemphigus foliaceus. Pemphigus vulgaris is the most common form. Pemphigus can occur at any age, but often strikes people in middle age or older.

Usually a chronic condition, pemphigus is best controlled by early diagnosis and treatment, which may include medications or treatments similar to those used for severe burns.

References
  1. Goldstein BG. Pemphigus. http://www.uptodate.com/index. Accessed Sept. 10, 2012.
  2. McPhee SJ, et al., eds. Current Medical Diagnosis and Treatment 2013. New York, N.Y.: McGraw-Hill Medical; 2013. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=1. Accessed September 12, 2012.
  3. Martin LK, et al. Interventions for pemphigus vulgaris and pemphigus foliaceus. Cochrane Database of Systematic Reviews. http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD006263.pub2/abstract. Accessed Sept. 12, 2012.
  4. Pemphigus. National Institute of Arthritis and Musculoskeletal and Skin Diseases. http://www.niams.nih.gov/health_info/pemphigus/. Accessed Sept. 10, 2012.
  5. Kasperkiewicz M, et al. Current therapy of the pemphigus group. Clinics in Dermatology. 2012;30:84.
  6. Venugopal SS, et al. Diagnosis and clinical features of pemphigus vulgaris. Dermatology Clinics. 2011;29:373.
DS00749 Nov. 7, 2012

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