CausesBy Mayo Clinic staff
Pemphigus is an autoimmune disorder, and in most cases, it's unknown what triggers the disease.
Normally, your immune system attacks foreign invaders, such as harmful viruses and bacteria. But in pemphigus, your immune system mistakenly produces antibodies that attack healthy cells in your skin and mucous membranes.
Sometimes, pemphigus develops as a side effect of certain medications, such as certain blood pressure drugs or chelating agents. This type of pemphigus usually disappears when the medicine is stopped.
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