Definition
By Mayo Clinic staffPeptic ulcers are open sores that develop on the inside lining of your esophagus, stomach and the upper portion of your small intestine. The most common symptom of a peptic ulcer is abdominal pain.
Peptic ulcers include:
- Gastric ulcers that occur on the inside of the stomach
- Esophageal ulcers that occur inside the hollow tube (esophagus) that carries food from your throat to your stomach
- Duodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum)
It's a myth that spicy foods or a stressful job can cause peptic ulcers. Doctors now know that a bacterial infection or some medications — not stress or diet — cause most peptic ulcers.
- Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed June 6, 2013.
- American College of Gastroenterology guidelines on the management of Helicobacter pylori infection. Bethesda, M.D.: American College of Gastroenterology. http://gi.org/guideline/management-of-helicobacter-pylori-infection. Accessed June 6, 2013.
- Rakel D. Integrative Medicine. 3rd ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.mdconsult.com/das/book/body/208746819-2/0/1494/0.html. Accessed June 6, 2013.
- H. pylori and peptic ulcers. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/index.htm. Accessed June 6, 2013.
- NSAIDs and peptic ulcers. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/nsaids/index.htm. Accessed June 6, 2013.
- Picco MF (expert opinion). Mayo Clinic, Jacksonville, Fla. June 14, 2013.
- Potassium. Natural Medicines Comprehensive Database. http://www.naturaldatabase.com. Accessed June 17, 2013.
- Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. May 21, 2013.


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