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Definition
By Mayo Clinic staff
Peptic ulcers are open sores that develop on the inside lining of your stomach, upper small intestine or esophagus. The most common symptom of a peptic ulcer is abdominal pain.
It wasn't too long ago that lifestyle factors, such as a love of spicy foods or a stressful job, were thought to be at the root of most peptic ulcers. Doctors now know that a bacterial infection or some medications — not stress or diet — cause most peptic ulcers.
Peptic ulcers are common, affecting as many as 10 percent of Americans at some point in their lives. The good news is that successful treatment of peptic ulcers is possible.
- H. pylori and peptic ulcer. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/. Accessed Oct. 16, 2008.
- What I need to know about peptic ulcers. National Digestive Diseases Information Clearinghouse. http://digestive.niddk.nih.gov/ddiseases/pubs/pepticulcers_ez/. Accessed Oct. 16, 2008.
- Peptic ulcer disease. American Gastroenterological Association. http://www.gastro.org/frame-templates/print_template.cfm. Accessed Oct. 16, 2008.
- Soll AH. Peptic ulcer disease: Genetic, environmental, and psychological risk factors and pathogenesis. http://www.uptodate.com/home/index.html. Accessed Oct. 16, 2008.
- Soll AH. Overview of peptic ulcer: Epidemiology and major causes. http://www.uptodate.com/home/index.html. Accessed Oct. 16, 2008.
- Lau JY. Omeprazole before endoscopy in patients with gastrointestinal bleeding. New England Journal of Medicine. 2007;356(16):1631-1640.
- Yang YX. Long-term proton pump inhibitor therapy and risk of hip fracture. Journal of the American Medical Association. 2007;296(24):2947-2953.
- Soll AH. Overview of the natural history and treatment of peptic ulcer disease. http://www.uptodate.com/home/index.html. Accessed Oct. 16, 2008.
- Soll AH. Treatment of refractory or recurrent peptic ulcer disease. http://www.uptodate.com/home/index.html. Accessed Oct. 16, 2008.
- Soll AH. Unusual causes of and diseases associated with peptic ulcer disease. http://www.uptodate.com/home/index.html. Accessed Oct. 16, 2008.
- Cryer B, et al. Peptic ulcer disease. In: Feldman M, et al. Sleisenger & Fortran's Gastrointestinal and Liver Disease. 8th ed. Philadelphia, Pa. Saunders Elsevier. http://www.mdconsult.com/das/book/body/113080343-3/781010342/1389/364.html#4-u1.0-B1-4160-0245-6..50055-X--cesec29_2206. Accessed Nov. 3, 2008.
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