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Symptoms
By Mayo Clinic staff
Pain is the most common symptom
Burning pain is the most common peptic ulcer symptom. The pain is caused by the ulcer and is aggravated by stomach acid coming in contact with the ulcerated area. The pain typically may:
- Be felt anywhere from your navel up to your breastbone
- Be worse when your stomach is empty
- Flare at night
- Often be temporarily relieved by eating certain foods that buffer stomach acid or by taking an acid-reducing medication
- Disappear and then return for a few days or weeks
Other signs and symptoms
Less often, ulcers may cause severe signs or symptoms such as:
- The vomiting of blood — which may appear red or black
- Dark blood in stools or stools that are black or tarry
- Nausea or vomiting
- Unexplained weight loss
- Appetite changes
When to see a doctor
See your doctor if you have persistent signs and symptoms that worry you. Over-the-counter antacids and acid blockers may relieve the gnawing pain, but the relief is short-lived. If your pain persists, see your doctor.
References
- Vakil N. Peptic ulcer disease. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed Dec. 1, 2010.
- Chan FK, et al. Treatment of peptic ulcer disease. In: Feldman M, et al. Sleisenger & Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, Management. 9th ed. Philadelphia, Pa.: Saunders Elsevier; 2010. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-1-4160-6189-2..X0001-7--TOP&isbn=978-1-4160-6189-2&about=true&uniqId=229935664-2192. Accessed Dec. 1, 2010.
- American College of Gastroenterology guidelines on the management of Helicobacter pylori infection. Bethesda, M.D.: American College of Gastroenterology. http://www.acg.gi.org/physicians/guidelines/ManagementofHpylori.pdf. Accessed Dec. 1, 2010.
- Podein R. Peptic ulcer disease. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Saunders; 2007. http://www.mdconsult.com/das/book/body/202281144-2/0/1494/0.html. Accessed Dec. 1, 2010.
- H. pylori and peptic ulcers. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/index.htm. Accessed Dec. 1, 2010.
- NSAIDs and peptic ulcers. National Institute for Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/nsaids/index.htm. Accessed Dec. 1, 2010.
- Picco MF (expert opinion). Mayo Clinic, Jacksonville, Fla. Dec. 8, 2010.
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