Definition
By Mayo Clinic staffCordocentesis — also known as percutaneous umbilical blood sampling — is a highly specialized prenatal test in which a sample of the baby's blood is removed from the umbilical cord for testing.
Cordocentesis can be used to detect certain blood conditions and infections. Cordocentesis can also be used to deliver blood transfusions and medication to a baby through the umbilical cord.
Use of cordocentesis is decreasing, however, since newer forms of technology can sometimes provide the same information from tests that pose a smaller risk of miscarriage — such as amniocentesis or chorionic villus sampling.
Cordocentesis might be offered when:
- The desired information can't be obtained any other way
- Results from other prenatal tests are unclear
- Test results might have a significant impact on the immediate management of the pregnancy
- Ghidini A. Fetal blood sampling. http://www.uptodate.com/index. Accessed Aug. 29, 2012.
- Grace D, et al. Training for percutaneous umbilical blood sampling during Maternal Fetal Medicine fellowship in the United States. Prenatal Diagnosis. 2009;29:790.
- Cunningham FG, et al. Williams Obstetrics. 23rd ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=46. Accessed Aug. 29, 2012.
- Collins SL, et al. Prenatal diagnosis: Types and techniques. Early Human Development. 2012;88:3.
- Harms RW (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 10, 2012.


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