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Risks

By Mayo Clinic staff

Cordocentesis carries potentially serious risks, including:

  • Pregnancy loss. Cordocentesis carries a higher risk of miscarriage than other prenatal diagnostic tests, such as chorionic villus sampling and amniocentesis. Some research estimates the risk as high as 3 percent for the general population. Since many babies are quite ill when the test is done, it's often difficult to determine whether fetal loss is related to the procedure itself or to the baby's health.
  • Bleeding. Bleeding from the area where the needle was inserted is possible.
  • Slowing of the baby's heart rate. The baby's heart rate might slow temporarily after cordocentesis.
  • Infection. Rarely, cordocentesis can lead to a uterine infection.

Ultimately, the decision to have cordocentesis is up to you. Your health care provider or genetic counselor can help you weigh all the factors in the decision.

References
  1. Ghidini A. Fetal blood sampling. http://www.uptodate.com/index. Accessed Aug. 29, 2012.
  2. Grace D, et al. Training for percutaneous umbilical blood sampling during Maternal Fetal Medicine fellowship in the United States. Prenatal Diagnosis. 2009;29:790.
  3. Cunningham FG, et al. Williams Obstetrics. 23rd ed. New York, N.Y.: The McGraw-Hill Companies; 2010. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=46. Accessed Aug. 29, 2012.
  4. Collins SL, et al. Prenatal diagnosis: Types and techniques. Early Human Development. 2012;88:3.
  5. Harms RW (expert opinion). Mayo Clinic, Rochester, Minn. Sept. 10, 2012.
MY00147 Oct. 13, 2012

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