Pericardial effusion

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Complications

By Mayo Clinic staff

The pericardium can hold only a limited amount of excess fluid without causing complications. The inner layer of the pericardium is made of a single layer of cells that sticks to the heart. The outer layer is thicker and only somewhat elastic. When the amount of liquid reaches a certain level, the pericardium expands inward, or toward the heart.

When pericardial effusion puts pressure on the heart, the pumping chambers of the heart fail to fill completely, and one or more chambers may partially collapse. This condition, called tamponade (tam-puh-NAYD), results in poor blood circulation and an inadequate supply of oxygen to the body. Tamponade is a life-threatening condition if left untreated.

References
  1. Little WC, et al. Pericardial disease. Circulation. 2006;113(12):1622-1632.
  2. Cardiopulmonary syndromes (PDQ®): Malignant pericardial effusion. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/supportivecare/cardiopulmonary/HealthProfessional. Accessed Nov. 1, 2008.
  3. Martin M, et al. Pericardial disease. In: Libby P, et al., eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/108738632-2/0/1549/0.html. Accessed Oct. 29, 2008.
  4. Khunnawat C, et al. Cardiovascular manifestations in human immunodeficiency virus-infected patients. American Journal of Cardiology. 2008;102(5):635-642.
  5. Maisch B, et al. Guidelines on the diagnosis and management of pericardial diseases executive summary: The task force on the diagnosis and management of pericardial diseases of the European Society of Cardiology. European Heart Journal. 2004;25(7):587-610.
  6. Ristic AD, et al. Management of pericardial effusion: The role of echocardiography in establishing the indications and the selection of the approach for drainage. Herz. 2005;30(2):144-150.

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Dec. 18, 2008

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