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Definition
By Mayo Clinic staff
Peripheral artery disease (also called peripheral arterial disease) is a common circulatory problem in which narrowed arteries reduce blood flow to your limbs.
When you develop peripheral artery disease (PAD), your extremities — usually your legs — don't receive enough blood flow to keep up with demand. This causes symptoms, most notably leg pain when walking (intermittent claudication).
Peripheral artery disease is also likely to be a sign of a more widespread accumulation of fatty deposits in your arteries (atherosclerosis). This condition may be reducing blood flow to your heart and brain, as well as your legs.
Often, you can successfully treat peripheral artery disease by quitting tobacco, exercising and eating a healthy diet.
- Peripheral artery disease. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec07/ch080/ch080f.html. Accessed May 8, 2012.
- Peripheral artery disease. National Heart, Lung, and Blood Institute. http://www.nhlbi.nih.gov/health/health-topics/topics/pad/. Accessed May 8, 2012.
- Mohler III ER. Clinical features, diagnosis, and natural history of lower extremity peripheral arterial disease. http://www.uptodate.com/index. Accessed May 8, 2012.
- Prevention and treatment of PAD. American Heart Association. http://www.heart.org/HEARTORG/Conditions/More/PeripheralArteryDisease/Prevention-and-Treatment-of-PAD_UCM_301308_Article.jsp. Accessed May 8, 2012.
- Hirsch AT, et al. ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease. Journal of the American College of Cardiology. 2006;47:e1.
- Rooke TW, et al. 2011 ACCF/AHA focused update of the guideline for the management of patients with peripheral arterial disease. Circulation. 2011;124:2020.
- Kuller LH. Does ginkgo biloba reduce the risk of cardiovascular events? Circulation: Cardiovascular Quality and Outcomes. 2010;3:41.
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