Risk factorsBy Mayo Clinic staff
Factors that increase your risk of developing peripheral artery disease include:
- Obesity (a body mass index over 30)
- High blood pressure (140/90 millimeters of mercury or higher)
- High cholesterol (total blood cholesterol over 240 milligrams per deciliter, or 6.2 millimoles per liter)
- Increasing age, especially after reaching 50 years of age
- A family history of peripheral artery disease, heart disease or stroke
- High levels of homocysteine, a protein component that helps build and maintain tissue
People who smoke or have diabetes have the greatest risk of developing peripheral artery disease due to reduced blood flow.
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