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Risk factors

By Mayo Clinic staff

Peripheral neuropathy risk factors include:

  • Diabetes, especially if your sugar levels are poorly controlled
  • Alcohol abuse
  • Vitamin deficiencies, particularly B vitamins
  • Infections, such as Lyme disease, shingles (varicella-zoster), Epstein-Barr, hepatitis C and HIV/AIDS
  • Autoimmune diseases, such as rheumatoid arthritis and lupus, in which the immune system attacks your own tissues
  • Kidney, liver or thyroid disorders
  • Exposure to toxins
  • Repetitive physical stress, possibly from occupational activities
References
  1. Peripheral neuropathy fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/peripheralneuropathy/detail_peripheralneuropathy.htm. Accessed Aug. 28, 2009.
  2. Peripheral nervous system and motor unit disorders. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merck.com/mmpe/print/sec16/ch223/ch223a.html. Accessed Aug. 29, 2009.
  3. Ropper AH, et al. Diseases of the peripheral nerves. In: Ropper AH, et al. Adams and Victor's Principles of Neurology. 9th ed. New York, N.Y.: McGraw-Hill Companies; 2009. http://www.accessmedicine.com/content.aspx?aID=3641268. Accessed Aug. 29, 2009.
  4. Feldman EL, et al. Treatment of diabetic neuropathy. http://www.uptodate.com/home/index.html. Accessed Aug. 18, 2009.
  5. Pai S. Peripheral neuropathy. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/156944782-3/0/1494/62.html#4-u1.0-B978-1-4160-2954-0..50019-3--cesec2_528. Accessed Aug. 29, 2009.
  6. Dietary supplement fact sheet: Vitamin B12. Office of Dietary Supplements. http://ods.od.nih.gov/factsheets/vitaminb12.asp. Accessed Aug. 28, 2009.

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Nov. 3, 2009

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