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Risk factors
By Mayo Clinic staffPeripheral neuropathy risk factors include:
- Diabetes, especially if your sugar levels are poorly controlled
- Alcohol abuse
- Vitamin deficiencies, particularly B vitamins
- Infections, such as Lyme disease, shingles (varicella-zoster), Epstein-Barr, hepatitis C and HIV/AIDS
- Autoimmune diseases, such as rheumatoid arthritis and lupus, in which your immune system attacks your own tissues
- Kidney, liver or thyroid disorders
- Exposure to toxins
- Repetitive physical stress, possibly from occupational activities
References
- Peripheral neuropathy fact sheet. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/peripheralneuropathy/detail_peripheralneuropathy.htm. Accessed Aug. 22, 2011.
- Peripheral neuropathy. The Merck Manuals: The Merck Manual for Healthcare Professionals. http://www.merckmanuals.com/professional/sec17/ch234/ch234h.html?qt=peripheral%20neuropathy&alt=sh#v1046209. Accessed Aug. 22, 2011.
- Pai S. Peripheral neuropathy. In: Rakel D. Integrative Medicine. 2nd ed. Philadelphia, Pa.: Saunders Elsevier; 2007. http://www.mdconsult.com/das/book/body/156944782-3/0/1494/62.html#4-u1.0-B978-1-4160-2954-0..50019-3--cesec2_528. Accessed Aug. 25, 2011.
- Dietary supplement fact sheet: Vitamin B12. Office of Dietary Supplements. http://ods.od.nih.gov/factsheets/vitaminb12.asp. Accessed Aug. 25, 2011.
- Bril V, et al. Evidence-based guideline: Treatment of painful diabetic neuropathy. Neurology. 2011;76:1758.
- Ropper AH, et al. Diseases of the peripheral nerves. In: Ropper AH, et al. Adams and Victor's Principles of Neurology. 9th ed. New York, N.Y.: McGraw-Hill Companies; 2009. http://www.accessmedicine.com/content.aspx?aID=3641268. Accessed Aug. 25, 2011.
- Amato AA, et al. Peripheral neuropathy. In: Fauci AS, et al. Harrison's Principals of Internal Medicine. 18th ed. New York, N.Y.: McGraw-Hill Companies; 2010. http://www.accessmedicine.com/content.aspx?aID=9148461. Accessed Aug. 25, 2011.
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