Original Article:  http://www.mayoclinic.com/health/petechiae/MY01104
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Definition

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Photograph of petechiae on leg and abdomen 
Petechiae

Petechiae (pronounced puh-TEE-kee-ee) are pinpoint, round spots that appear on the skin as a result of bleeding under the skin. The bleeding causes the petechiae to appear red, brown or purple. Petechiae commonly appear in clusters and may look like a rash. Usually flat to the touch, petechiae don't lose color when you press on them.

Petechiae are tiny, usually measuring less than an eighth of an inch (about 3 millimeters). Larger varieties of these types of spots are called purpura. Petechiae may indicate a number of conditions, ranging from minor blood vessel injuries to life-threatening medical conditions.

Causes

Tiny blood vessels (capillaries) link the smallest parts of your arteries to the smallest parts of your veins. Petechiae appear when capillaries bleed, leaking blood into the skin. A number of things — including prolonged straining, certain medical conditions, specific types of injuries and some medications — can cause this bleeding.

Prolonged straining
Tiny petechiae of the face, neck and chest can be caused by prolonged straining during activities such as:

  • Crying
  • Coughing
  • Vomiting
  • Childbirth
  • Weightlifting

Certain medications
Some types of medications can result in petechiae, including:

  • Aspirin
  • Atropine (Atropen)
  • Carbamazepine (Carbatrol, Epitol, Tegretol, others)
  • Chloral hydrate (Somnote)
  • Cimetidine (Tagamet)
  • Desipramine (Norpramin)
  • Indomethacin (Indocin)
  • Morphine (Avinza, Ms Contin, others)
  • Naproxen (Aleve, Anaprox, Naprosyn)
  • Nitrofurantoin (Furadantin, Macrobid, Macrodantin)
  • Penicillin
  • Quinine (Qualaquin)

Infectious diseases
Some types of infectious diseases can cause petechiae on the skin, while others may result in petechiae on the inner surfaces of the mouth or eyelids. A variety of fungal, viral and bacterial infections can cause petechiae, including:

Other medical conditions
Many noninfectious medical conditions also can cause petechiae. Examples include:

When to see a doctor

See your doctor promptly if you or your child develops unexplained or widespread petechiae. It's important to determine the cause, since some underlying problems can be potentially serious.

References
  1. Paulman PM, et al. Taylor's 10-minute Diagnosis Manual: Symptoms and Signs in the Time-Limited Encounter. 2nd ed. Philadelphia, Pa.: Lippincott Williams & Wilkins; 2007:343.
  2. Mandell GL, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06839-3..X0001-X--TOP&isbn=978-0-443-06839-3&uniqId=230100505-57. Accessed Feb. 20, 2012.
  3. Goldman L, et al. Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2011. http://www.mdconsult.com/das/book/body/191371208-2/0/1492/0.html#. Accessed Feb. 20, 2012.
  4. Hoffman R, et al. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2009. http://www.mdconsult.com/books/about.do?about=true&eid=4-u1.0-B978-0-443-06715-0..X5001-8--TOP&isbn=978-0-443-06715-0&uniqId=230100505-56. Accessed Feb. 20, 2012.
  5. Anderson CF (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 22, 2012.
MY01104 May 5, 2012

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