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Risk factors
By Mayo Clinic staffMinor injury to the penis doesn't always lead to Peyronie's disease. There are a number of factors that can contribute to poor wound healing, and these factors may play a role in Peyronie's disease. These include:
- Heredity. If your father or brother has Peyronie's disease, you have an increased risk of the disorder.
- Connective tissue disorders. Men who have a connective tissue disorder appear to have a greater risk of developing Peyronie's disease. For example, a condition known as Dupuytren's contracture — a cord-like thickening across the palm that causes the fingers to pull inward — is common in men with Peyronie's disease.
- Age. The prevalence of Peyronie's disease increases with age. Age-related changes in tissues may cause them to be prone to injury, less likely to heal well, or both.
Other factors
Other factors associated with an increased risk of Peyronie's disease include:
- Diabetes
- Tobacco use
- History of pelvic injury
- Peyronie's disease. American Urological Association Foundation. http://urologyhealth.org/adult/index.cfm?cat=11&topic=50. Accessed June 3, 2009.
- Briganti A, et al. Peyronie's disease: A review. Current Opinion in Urology. 2003;13:417.
- Taylor FL, et al. Peyronie's Disease. Urological Clinics of North America. 2007;34:517.
- Sommer F, et al. Epidemiology of Peyronie's disease. International Journal of Impotence Research. 2002;14:379.
- Trost LW, et al. Pharmacological management of Peyronie's disease. Drugs. 2007;67:527.
