Pituitary tumors

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Complications

By Mayo Clinic staff

Pituitary tumors usually don't grow or spread extensively. However, they can adversely affect your health, possibly causing:

  • Vision loss. A pituitary tumor can put pressure on the optic nerves, which are close to your pituitary gland, and cause loss of vision.
  • Permanent hormone deficiency. The presence of a pituitary tumor or the removal of one may permanently alter your hormone supply, which may need to be replaced with hormone medications.
  • Diabetes insipidus. This is a possible complication of a large pituitary tumor or of some treatments for pituitary tumors. Not to be confused with the more common diabetes mellitus, which involves high sugar levels in the blood and urine, diabetes insipidus is the result of the pituitary making too little vasopressin, which controls the concentration of urine in the kidneys. Diabetes insipidus causes excess amounts of urine and severe thirst, which can lead to dehydration.

A rare but potentially serious complication of a pituitary tumor is pituitary apoplexy, when sudden bleeding into the tumor occurs. Pituitary apoplexy requires emergency treatment, usually with corticosteroids and possibly surgery.

References
  1. Pituitary tumors information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/pituitary_tumors/pituitary_tumors.htm. Accessed Aug. 6, 2012.
  2. Pituitary tumors. American Cancer Society. http://www.cancer.org/Cancer/PituitaryTumors/DetailedGuide/index. Accessed Aug. 6, 2012.
  3. Pituitary tumors treatment — Health professional version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/pituitary/HealthProfessional. Accessed Aug. 6, 2012.
  4. Ferri FF. Ferri's Clinical Advisor 2013: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2012. http://www.mdconsult.com/books/about.do?eid=4-u1.0-B978-0-323-08373-7..00002-9&isbn=978-0-323-08373-7&about=true&uniqId=343863096-23. Accessed Aug. 6, 2012.
  5. Pituitary tumors treatment — Patient version. National Cancer Institute. http://www.cancer.gov/cancertopics/pdq/treatment/pituitary/Patient. Accessed Aug. 6, 2012.
  6. Erickson DX (expert opinion). Mayo Clinic, Rochester, Minn. Aug. 21, 2012. 
  7. Parlodel (prescribing information). East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2012. http://www.pharma.us.novartis.com/product/pi/pdf/parlodel.pdf. Accessed Nov. 13, 2012.
  8. Cycloset (prescribing information). San Diego, Calif.: VeroScience, LLC; 2010. http://www.veroscience.com/CyclosetFDAapprovedPackageInsert.htm. Accessed Nov. 13, 2012.
  9. Cabergoline (prescribing information). Sellersville, Pa.: Teva Pharmaceuticals; 2012. http://www.tevagenerics.com/default.aspx?pageid=3364&sortby=ProductName&ProductName=Cabergoline+Tablets&BrandName=Dostinex%C2%AE+Tablets. Accessed Nov. 13, 2012.
  10. Martinkova J, et al. Impulse control disorders associated with dopaminergic medication in patients with pituitary adenomas. Clinical Neuropharmacology. 2011;34:179.
DS00533 Nov. 14, 2012

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